product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-Annexin VI Antibody
catalog :
PA1436
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
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product information
Product Name :
Anti-Annexin VI Antibody
Catalog Number :
PA1436
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Annexin A6(ANXA6) detection. Tested with WB, IHC-P, IHC-F in Human;Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human, rat
Predicted to work with: mouse
Applications :
WB,IHC-P,IHC-F
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse
Immunohistochemistry(Frozen Section) :
Concentration: 0.5-1μg/ml; Tested Species: Rat; Predicted Species: Human, Mouse
Notes :
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of human Annexin VI(636-652aa NIRREFIEKYDKSLHQA), identical to the related mouse and rat sequences.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P) and IHC(F).
Background :
Annexin A6(ANXA6) is a member of a family of proteins that bind membrane or cytoskeleton in a Ca(2+)-dependent manner. These proteins are characterized by homologous amino acid sequences that are present in multiple copies in each protein. ANXA6 gene is assigned to 5q32-q34 by use of a cDNA clone to probe genomic DNA from rodent-human somatic cell hybrids and for in situ hybridization.The ANX6 gene is approximately 60 kb long and contains 26 exons. The genomic sequence at the 3-prime end does not contain a canonical polyadenylylation signal.Ca(2+)-dependent binding between CRHSP28 and ANXA6 is required for acinar cell membrane trafficking events and digestive enzyme secretion
Reference :
1. Davies, A. A., Moss, S. E., Crompton, M. R., Jones, T. A., Spurr, N. K., Sheer, D., Kozak, C., Crumpton, M. J.The gene coding for the p68 calcium-binding protein is localized to bands q32-q34 of human chromosome 5, and to mouse chromosome 11.Hum. Genet. 82: 234-238, 1989.
2. Smith, P. D., Davies, A., Crumpton, M. J., Moss, S. E.Structure of the human annexin VI gene.Proc. Nat. Acad. Sci. 91: 2713-2717, 1994.
3. Thomas, D. D. H., Kaspar, K. M., Taft, W. B., Weng, N., Rodenkirch, L. A., Groblewski, G. E.Identification of annexin VI as a Ca(2+)-sensitive CRHSP-28-binding protein in pancreatic acinar cells.J. Biol. Chem. 277: 35496-35502, 2002.
Gene Name :
ANXA6
Protein Name :
Annexin A6
Gene Full Name :
annexin A6
Synonyms :
67 kDa calelectrin antibody Annexin A6 antibody Annexin VI antibody Annexin VI p68 antibody Annexin-6 antibody AnnexinA6 antibody AnnexinVI antibody ANX 6 antibody ANX A6 antibody ANX6 antibody ANXA 6 antibody ANXA6 antibody ANXA6_HUMAN antibody Calcium binding protein p68 antibody Calelectrin antibody Calphobindin II antibody Calphobindin-II antibody CalphobindinII antibody CBP 68 antibody CBP68 antibody Chromobindin 20 antibody Chromobindin-20 antibody Chromobindin20 antibody CPB II antibody CPB-II antibody CPBII antibody Lipocortin VI antibody LipocortinVI antibody p68 antibody p70 antibody Protein III antibody ProteinIII antibody
Uniprot ID :
P08133
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
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