product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-TRAIL Antibody
catalog :
PA1419
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
mouse, rat
application :
western blot, immunohistochemistry - paraffin section
product information
Product Name :
Anti-TRAIL Antibody
Catalog Number :
PA1419
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Tumor necrosis factor ligand superfamily member 10(TNFSF10) detection. Tested with WB, IHC-P in Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: mouse, rat
Applications :
WB,IHC-P
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Mouse; Predicted Species: Rat
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Mouse, Rat
Notes :
WB: The detection limit for TNFSF10 is approximately 1ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of mouse TRAIL(272-291aa NEHLMDLDQEASFFGAFLIN), different from the related rat sequence by one amino acid.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).
Background :
Tumor necrosis factor receptor superfamily member 1A(TNFRSF1A) is a protein that in humans is encoded by the TNFRSF1A gene. The protein encoded by this gene is a member of the Tumor necrosis factor receptor superfamily, which also contains TNFRSF1B. The TNFR1 gene is mapped to 12pter-cen. it encodes a protein of 455 amino acids. This receptor can activate the transcription factor NF-KB, mediate apoptosis, and function as a regulator of inflammation.
Reference :
1. Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, Sutherland GR, Smith TD, Rauch C, Smith CA (December 1995). "Identification and characterization of a new member of the TNF family that induces apoptosis". Immunity 3 (6): 673–82. 2. Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A (May 1996). "Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family". J. Biol. Chem. 271 (22): 12687–90. 3. Song JJ, Lee YJ (May 2008). "Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily". Cell. Signal. 20 (5): 892–906.
Gene Name :
TNFSF10
Protein Name :
Tumor necrosis factor ligand superfamily member 10
Gene Full Name :
tumor necrosis factor(ligand) superfamily, member 10
Synonyms :
Apo 2 ligand antibody Apo 2L antibody Apo-2 ligand antibody Apo-2L antibody APO2L antibody CD 253 antibody CD253 antibody CD253 antigen antibody Chemokine tumor necrosis factor ligand superfamily member 10 antibody Protein TRAIL antibody TL 2 antibody TL2 antibody TNF Related Apoptosis Inducing Ligand antibody TNF related apoptosis inducing ligand TRAIL antibody TNF-related apoptosis-inducing ligand antibody TNF10_HUMAN antibody TNFSF 10 antibody TNFSF10 antibody TNFSF10 protein antibody TRAIL antibody TRAIL PEN antibody Tumor necrosis factor(ligand) family member 10 antibody Tumor Necrosis Factor(ligand) Superfamily Member 10 antibody Tumor necrosis factor apoptosis inducing ligand splice variant delta antibody Tumor necrosis factor ligand superfamily member 10 antibody
Uniprot ID :
P50592
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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