Anti-PI 3 Kinase p85 alpha Antibody | Boster Immunoleader PA1410 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-PI 3 Kinase p85 alpha Antibody

catalog :

PA1410

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

publications citing this reagent :

Wang Y, Lv H, Hao Y, Zhang H, Li L, Cai G, et al. Suppressive oligodeoxynucleotides induced tolerogenic plasmacytoid dendritic cells and ameliorated the experimental autoimmune neuritis. Immunol Lett. 2015;166:13-8 pubmed publisher

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-PI 3 Kinase p85 alpha Antibody

Catalog Number :

PA1410

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Phosphatidylinositol 3-kinase regulatory subunit alpha(PIK3R1) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human PI 3 Kinase p85 alpha(65-80aa ERGDFPGTYVEYIGRK), identical to the related rat and mouse sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Phosphatidylinositol 3-kinase regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene. Its gene is mapped to 5q13. the bovine PI3K p85 subunit consists of 2 closely related proteins, p85-alpha and p85-beta. They cloned cDNAs encoding both p85 subunits, each of which is a 724-amino acid polypeptide. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance.

Reference :

1. Volinia S, Patracchini P, Otsu M, Hiles I, Gout I, Calzolari E, Bernardi F, Rooke L, Waterfield MD (May 1992). "Chromosomal localization of human p85 alpha, a subunit of phosphatidylinositol 3-kinase, and its homologue p85 beta". Oncogene 7 (4): 789–93. PMID 1314371. 2. Cannizzaro, L. A., Skolnik, E. Y., Margolis, B., Croce, C. M., Schlesinger, J., Huebner, K.The human gene encoding phosphatidylinositol 3-kinase associated p85-alpha is at chromosome region 5q12-13.Cancer Res.51: 3818-3820, 1991.

Gene Name :

PIK3R1

Protein Name :

Phosphatidylinositol 3-kinase regulatory subunit alpha(PI3-kinase regulatory subunit alpha/PI3K regulatory subunit alpha/PtdIns-3-kinase regulatory subunit alpha)

Gene Full Name :

phosphoinositide-3-kinase, regulatory subunit 1(alpha)

Synonyms :

GRB 1 antibody GRB1 antibody p85 alpha antibody p85 antibody p85a antibody P85A_HUMAN antibody Phosphatidylinositol 3 kinase associated p 85 alpha antibody Phosphatidylinositol 3 kinase associated p85 alpha antibody Phosphatidylinositol 3 kinase regulatory 1 antibody Phosphatidylinositol 3 kinase regulatory alpha subunit antibody Phosphatidylinositol 3 kinase regulatory subunit alpha antibody Phosphatidylinositol 3 kinase regulatory subunit polypeptide 1 antibody Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 1(p85 alpha) antibody Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha antibody Phosphatidylinositol 3-kinase regulatory subunit alpha antibody Phosphoinositide 3 kinase regulatory subunit 1 antibody Phosphoinositide 3 kinase regulatory subunit polypeptide 1(p85 alpha) antibody Phosphoinositide 3 kinase regulatory subunit polypeptide 1 antibody Phosphoinositide 3 kinase, regulatory subunit 1(alpha) antibody PI3 kinase p85 alpha subunit antibody PI3 kinase p85 subunit alpha antibody PI3-kinase regulatory subunit alpha antibody PI3-kinase subunit p85-alpha antibody PI3K antibody PI3K regulatory subunit alpha antibody PIK3R 1 antibody PIK3R1 antibody PtdIns 3 kinase p85 alpha antibody PtdIns-3-kinase regulatory subunit alpha antibody PtdIns-3-kinase regulatory subunit p85-alpha antibody

Uniprot ID :

P27986

more info or order :

Boster Immunoleader product webpage