product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-IGFBP6 Antibody
catalog :
PA1404
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot
product information
Product Name :
Anti-IGFBP6 Antibody
Catalog Number :
PA1404
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 6(IGFBP6) detection. Tested with WB in Human;Mouse;Rat.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human, rat Predicted to work with: mouse
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse
Notes :
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence in the middle region of human IGFBP6(189-205aa NCDHRGFYRKRQCRSSQ), different from the related rat sequence by two amino acids.
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
Insulin-like growth factor-binding protein 6(IGFBP6) is a protein that in humans is encoded by the IGFBP6 gene. The IGFBP6 gene is mapped to chromosome 12. In all, it has contained 216 amino acid protein with a calculated molecular mass of 22,847 Da. Kato et al.(1995) showed that the human keratinocyte cell line HaCat secretes IGFBP6 as an autocrine growth inhibitor. Recombinant IGFBP6 was also shown to inhibit growth of HaCat cells and other keratinocyte cell lines.
Reference :
1. Kiefer MC, Ioh RS, Bauer DM, Zapf J (May 1991). "Molecular cloning of a new human insulin-like growth factor binding protein". Biochem Biophys Res Commun 176 (1): 219–25. doi:10.1016/0006-291X(91)90912-Q. PMID 1850258. 2. Ehrenborg E, Zazzi H, Lagercrantz S, Granqvist M, Hillerbrand U, Allander SV, Larsson C, Luthman H (May 1999). "Characterization and chromosomal localization of the human insulin-like growth factor-binding protein 6 gene". Mamm Genome 10 (4): 376–80. doi:10.1007/s003359901005. PMID 10087296. 3. Entrez Gene: IGFBP6 insulin-like growth factor binding protein 6".
Gene Name :
IGFBP6
Protein Name :
Insulin-like growth factor-binding protein 6(IBP-6/IGF-binding protein 6/IGFBP-6)
Gene Full Name :
insulin-like growth factor binding protein 6
Synonyms :
IBP 6 antibody IBP-6 antibody IBP6 antibody IBP6_HUMAN antibody IGF binding protein 6 antibody IGF-binding protein 6 antibody IGFBP 6 antibody IGFBP-6 antibody IGFBP6 antibody Insulin like growth factor binding protein 6 antibody Insulin-like growth factor-binding protein 6 antibody
Uniprot ID :
P24592
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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