Anti-CX3CL1 Antibody | Boster Immunoleader PA1400 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-CX3CL1 Antibody

catalog :

PA1400

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

publications citing this reagent :

Xu Y, Zeng K, Han Y, Wang L, Chen D, Xi Z, et al. Altered expression of CX3CL1 in patients with epilepsy and in a rat model. Am J Pathol. 2012;180:1950-62 pubmed publisher

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-CX3CL1 Antibody

Catalog Number :

PA1400

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Fractalkine(CX3CL1) detection. Tested with WB in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human CX3CL1(50-64aa HYQQNQASCGKRAII).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Chemokine(C-X3-C motif) ligand 1, also known as CX3CL1, is a large cytokine protein. It is said to be the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine(in humans) and neurotactin(in mice). Its gene is mapped to the long arm of chromosome 8. Being the large protein, it has got 373 amino acids. Imai et al.(1997) identified a 7-transmembrane high-affinity receptor(CX3CR1; 601470) for fractalkine and showed that it mediates both the adhesive and migratory functions of fractalkine.

Reference :

1. Pan et al., Lloyd C, Zhou H, Dolich S, Deeds J, Gonzalo JA, Vath J, Gosselin M et al. (1997). "Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation". Nature 387 (6633): 611–617. 2. Bazan et al., Bacon KB, Hardiman G, Wang W, Soo K, Rossi D, Greaves DR, Zlotnik A et al. (1997). "A new class of membrane-bound chemokine with a CX3C motif". Nature 385 (6617): 640–644. doi:10.1038/385640a0. PMID 9024663. 3. Hannan, N. J., Jones, R. L., Critchley, H. O. D., Kovacs, G. J., Rogers, P. A. W., Affandi, B., Salamonsen, L. A.Coexpression of fractalkine and its receptor in normal human endometrium and in endometrium from users of progestin-only contraception supports a role of fractalkine in leukocyte recruitment and endometrial remodeling.J. Clin. Endocr. Metab.89: 6119-6129, 2004.

Gene Name :

CX3CL1

Protein Name :

Fractalkine

Gene Full Name :

chemokine(C-X3-C motif) ligand 1

Synonyms :

A 152E5.2 antibody AB030188 antibody ABCD 3 antibody ABCD3 antibody AI848747 antibody C-X3-C motif chemokine 1 antibody C3Xkine antibody Chemokine(C-X3-C motif) ligand 1 antibody Chemokine C X3 C motif ligand 1 antibody Chemokine CX3C Motif Ligand 1 antibody CX3C membrane anchored chemokine antibody CX3C membrane-anchored chemokine antibody CX3CL1 antibody CXC 3 antibody CXC3 antibody CXC3C antibody D8Bwg0439e antibody FKN antibody Fractalkine antibody Neurotactin antibody NTN antibody NTT antibody Processed fractalkine antibody SCYD 1 antibody SCYD1 antibody Small inducible cytokine D1 antibody Small inducible cytokine subfamily D(Cys X3 Cys) member 1 antibody small inducible cytokine subfamily D(Cys-X3-Cys), member 1(fractalkine, neurotactin) antibody Small inducible cytokine subfamily D member 1 antibody Small-inducible cytokine D1 antibody X3CL1_HUMAN antibody

Uniprot ID :

P78423

more info or order :

Boster Immunoleader product webpage