product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-VEGF Receptor 1 Antibody
catalog :
PA1399
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot
product information
Product Name :
Anti-VEGF Receptor 1 Antibody
Catalog Number :
PA1399
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Vascular endothelial growth factor receptor 1(FLT1) detection. Tested with WB in Human.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human
Applications :
WB
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human
Notes :
WB: The detection limit for FLT1 is approximately 0.5ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of human VEGF Receptor 1(1299-1317aa HVSEGKRRFTYDHAELERK).
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.
Background :
Vascular endothelial growth factor receptor 1(FLT1) is a protein that in humans is encoded by the FLT1 gene. Oncogene FLT belongs to the src gene family. It is mapped to 13q12. The deduced 1,338-amino acid protein has a calculated molecular mass of 150.6 kD. It has a 758-amino acid extracellular domain, followed by a 22-amino acid transmembrane region and a 558-amino acid cytoplasmic region containing a cluster of basic amino acids and a tyrosine kinase domain. sFLT-1 was identified in placenta, adult lung, kidney, liver and uterus. Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation.
Reference :
1. Shibuya M, Yamaguchi S, Yamane A, Ikeda T, Tojo A, Matsushime H, Sato M (May 1990). "Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family". Oncogene 5 (4): 519–24. PMID 2158038. 2. Entrez Gene: FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)". 3. He, Y., Smith, S. K., Day, K. A., Clark, D. E., Licence, D. R., Charnock-Jones, D. S.Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity.Molec. Endocr.13: 537-545, 1999.
Gene Name :
FLT1
Protein Name :
Vascular endothelial growth factor receptor 1(VEGFR-1)
Gene Full Name :
fms-related tyrosine kinase 1(vascular endothelial growth factor/vascular permeability factor
Synonyms :
EC 2.7.10.1 antibody Flt 1 antibody FLT antibody Flt-1 antibody Flt1 antibody Fms like tyrosine kinase 1 antibody Fms related tyrosine kinase 1(vascular endothelial growth factor/vascular permeability factor receptor) antibody Fms related tyrosine kinase 1 antibody Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor antibody Fms-like tyrosine kinase 1 antibody FRT antibody Soluble VEGF receptor 1 14 antibody Soluble VEGFR1 variant 2 antibody Soluble VEGFR1 variant 21 antibody Tyrosine protein kinase FRT antibody Tyrosine protein kinase receptor FLT antibody Tyrosine-protein kinase FRT antibody Tyrosine-protein kinase receptor FLT antibody Vascular endothelial growth factor receptor 1 antibody Vascular endothelial growth factor receptor 1 Precursor antibody Vascular endothelial growth factor vascular permeability factor receptor antibody Vascular permeability factor receptor 1 antibody Vascular permeability factor receptor antibody VEGFR 1 antibody VEGFR-1 antibody VEGFR1 antibody VGFR1_HUMAN antibody
Uniprot ID :
P17948
company information
Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com
925.485.4527
headquarters: USA
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