product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-IP10 Antibody
catalog :
PA1396
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot, immunohistochemistry - paraffin section
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product information
Product Name :
Anti-IP10 Antibody
Catalog Number :
PA1396
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for C-X-C motif chemokine 10(CXCL10) detection. Tested with WB, IHC-P in Human.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: human
Applications :
WB,IHC-P
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Human
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Human
Notes :
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of human IP10(79-98aa SKAIKNLLKAVSKERSKRSP).
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).
Background :
C-X-C motif chemokine 10(CXCL10), also known as Interferon gamma-induced protein 10 kDa(IP-10) or small-inducible cytokine B10, is a protein that in humans is encoded by the CXCL10 gene. It is a small cytokine belonging to the CXC chemokine family. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. Luster et al.(1987) reported the isolation of an interferon-inducible gene that encodes a 98-amino acid protein called IP10. The chemokine IFN-gamma-inducible protein 10(IP-10; CXCL10), a CXC chemokine, and its receptor, CXCR3, were found to be overexpressed in lymph node cells of EAMG rats. IP10 inhibits bone marrow colony formation, has antitumor activity in vivo, is a chemoattractant for human monocytes and T cells, and promotes T cell adhesion to endothelial cells.
Reference :
1. Luster AD, Unkeless JC, Ravetch JV (1985). "Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins". Nature 315 (6021): 672–6.
2. Luster AD, Jhanwar SC, Chaganti RS, Kersey JH, Ravetch JV (May 1987). "Interferon-inducible gene maps to a chromosomal band associated with a (4;11) translocation in acute leukemia cells". Proc. Natl. Acad. Sci. U.S.A. 84 (9): 2868–71.
3. Feferman, T., Maiti, P. K., Berrih-Aknin, S., Bismuth, J., Bidault, J., Fuchs, S., Souroujon, M. C.Overexpression of IFN-induced protein 10 and its receptor CXCR3 in myasthenia gravis.J. Immun.174: 5324-5331, 2005.
Gene Name :
CXCL10
Protein Name :
C-X-C motif chemokine 10
Gene Full Name :
chemokine(C-X-C motif) ligand 10
Synonyms :
10 kDa interferon gamma induced protein antibody 10 kDa interferon gamma-induced protein antibody C X C motif chemokine 10 antibody C7 antibody Chemokine(C X C motif) ligand 10 antibody Chemokine CXC motif ligand 10 antibody Crg 2 antibody CRG2 antibody CXCL 10 antibody CXCL10 antibody CXCL10(1-73) antibody CXL10_HUMAN antibody Gamma IP10 antibody Gamma-IP10 antibody gIP 10 antibody GIP10 antibody IFI 10 antibody IFI10 antibody INP 10 antibody INP10 antibody Interferon activated gene 10 antibody Interferon gamma induced cell line antibody Interferon inducible cytokine IP 10 antibody Interferon inducible cytokine IP10 antibody IP 10 antibody IP-10 antibody Mob 1 antibody MOB1 antibody Protein 10 from interferon(gamma) induced cell line antibody SCYB 10 antibody SCYB10 antibody Small inducible cytokine B10 antibody Small inducible cytokine B10 precursor antibody Small inducible cytokine subfamily B(Cys X Cys) member 10 antibody Small inducible cytokine subfamily B CXC member 10 antibody Small-inducible cytokine B10 antibody
Uniprot ID :
P02778
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
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