Anti-TIMP1 Antibody | Boster Immunoleader PA1385 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-TIMP1 Antibody

catalog :

PA1385

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, immunohistochemistry - paraffin section

publications citing this reagent :

Zhou Y, Tan X, Kuang W, Liu L, Wan L. Erythromycin ameliorates cigarette-smoke-induced emphysema and inflammation in rats. Transl Res. 2012;159:464-72 pubmed publisher

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-TIMP1 Antibody

Catalog Number :

PA1385

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Metalloproteinase inhibitor 1(TIMP1) detection. Tested with WB, IHC-P in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP1(189-207aa CLPREPGLCTWQSLRSQIA).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases(MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. TIMP was found to be located about 22 cM proximal to OTC(300461).

Reference :

1. TIMP1 TIMP metallopeptidase inhibitor 1

Gene Name :

TIMP1

Protein Name :

Metalloproteinase inhibitor 1

Gene Full Name :

TIMP metallopeptidase inhibitor 1

Synonyms :

Clgi antibody Collagenase inhibitor antibody EPA antibody EPO antibody Erythroid Potentiating Activity antibody Erythroid-potentiating activity antibody Fibroblast collagenase inhibitor antibody FLJ90373 antibody HCI antibody Human Collagenase Inhibitor antibody Metalloproteinase inhibitor 1 antibody Metalloproteinase inhibitor 1 precursor antibody OTTHUMP00000023214 antibody TIMP 1 antibody TIMP antibody TIMP metallopeptidase inhibitor 1 antibody TIMP-1 antibody Timp1 antibody TIMP1 protein antibody TIMP1_HUMAN antibody Tissue Inhibitor of Metalloproteinase 1 antibody Tissue inhibitor of metalloproteinases 1 antibody Tissue inhibitor of metalloproteinases antibody Ttissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor antibody

Uniprot ID :

P01033

more info or order :

Boster Immunoleader product webpage