Boster Immunoleader

antibody

Anti-RANK Antibody

PA1382

100 ug/vial

200 USD

polyclonal

rabbit

western blot, immunohistochemistry - paraffin section

Anti-RANK Antibody

PA1382

Polyclonal

Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 11A(TNFRSF11A) detection. Tested with WB, IHC-P in Human.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Concentration: 0.5-1μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the N-terminus of human RANK(29-44aa QIAPPCTSEKHYEHLG).

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Receptor Activator of Nuclear Factor K B(RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling. RANKL(Receptor Activator for Nuclear Factor K B Ligand) is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, Anderson et al.(1997) mapped the RANK gene to 18q22.1.

1. Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ (1999). "Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families". Endocr. Rev. 20 (3): 345–57. 2. Wong BR, Josien R, Choi Y (1999). "TRANCE is a TNF family member that regulates dendritic cell and osteoclast function". J. Leukoc. Biol. 65 (6): 715–24. 3. Theill LE, Boyle WJ, Penninger JM (2002). "RANK-L and RANK: T cells, bone loss, and mammalian evolution". Annu. Rev. Immunol. 20: 795–823.

TNFRSF11A

Tumor necrosis factor receptor superfamily member 11A

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Activator of NFKB antibody CD 265 antibody CD265 antibody CD265 antigen antibody EOF antibody FEO antibody LOH18CR1 antibody Loss of heterozygosity 18 chromosomal region 1 antibody mRANK antibody NFKB activator antibody ODFR antibody OFE antibody OPTB7 antibody Osteoclast differentiation factor receptor antibody OSTS antibody PDB 2 antibody PDB2 antibody RANK antibody Receptor activator of NF KB antibody Receptor activator of NF-KB antibody receptor activator of nuclear factor kappa B antibody TNFRSF 11A antibody TNFRSF11A antibody TNFSF11 antibody TNR11_HUMAN antibody TRANCE R antibody TRANCER antibody Tumor necrosis factor receptor superfamily member 11a NFKB activator antibody Tumor necrosis factor receptor superfamily member 11a activator of NFKB antibody Tumor Necrosis Factor Receptor Superfamily Member 11a antibody

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