product summary
request information :
company name :
Boster Immunoleader
product type :
antibody
product name :
Anti-IL1 alpha Antibody
catalog :
PA1375
quantity :
100 ug/vial
price :
200 USD
clonality :
polyclonal
host :
rabbit
reactivity :
mouse
application :
western blot, immunohistochemistry - paraffin section
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product information
Product Name :
Anti-IL1 alpha Antibody
Catalog Number :
PA1375
Clonality :
Polyclonal
Description short :
Rabbit IgG polyclonal antibody for Interleukin-1 alpha(IL1A) detection. Tested with WB, IHC-P in Mouse.
Price :
200 USD
Ig type :
Rabbit IgG
Size :
100 ug/vial
Form :
Lyophilized
Specificity :
No cross reactivity with other proteins.
Reactivity :
Reacts with: mouse
Applications :
WB,IHC-P
Western blot :
Concentration: 0.1-0.5μg/ml; Tested Species: Mouse
Immunohistochemistry(Paraffin-embedded S ... :
Concentration: 0.5-1μg/ml; Tested Species: Mouse
Notes :
Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen :
A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL1 alpha(256-270aa HLARGLPSMTDFQIS).
Contents :
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Purification :
Immunogen affinity purified.
Reconstitution :
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage :
At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Relevant detection systems :
Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).
Background :
Interleukin-1 alpha(IL-1alpha) is a protein that in humans is encoded by the IL1A gene. The protein encoded by this gene is a cytokine of the interleukin-1 family. Interleukin-1 alpha possesses a wide spectrum of metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. Silver et al.(1990) showed that the mouse Il1a and Il1b genes are contained in a genomic fragment of about 70 kb. Further studies suggested that Il1b lies 5-prime to Il1a, that the 2 genes are oriented in the same direction, and that they are separated by about 50 kb.
Reference :
1. Nicklin MJ, Weith A, Duff GW (Jun 1994). "A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist genes". Genomics 19 (2): 382–4.
2. March CJ, Mosley B, Larsen A, Cerretti DP, Braedt G, Price V, Gillis S, Henney CS, Kronheim SR, Grabstein K, et al. (Aug 1985). "Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs". Nature 315 (6021): 641–7.
3. Bankers-Fulbright JL, Kalli KR, McKean DJ (1996). "Interleukin-1 signal transduction". Life Sci. 59 (2): 61–83.
4. Dinarello CA (June 1997). "Induction of interleukin-1 and interleukin-1 receptor antagonist". Semin. Oncol. 24 (3 Suppl 9): S9–81–S9–93.
Gene Name :
IL1A
Protein Name :
Interleukin-1 alpha(IL-1 alpha)
Gene Full Name :
interleukin 1, alpha
Synonyms :
BAF antibody FAF antibody Hematopoietin 1 antibody Hematopoietin-1 antibody IL 1 alpha antibody IL 1 antibody IL 1A antibody IL-1 alpha antibody Il-1a antibody IL1 ALPHA antibody IL1 antibody IL1A antibody IL1A_HUMAN antibody IL1F1 antibody ilia antibody Interleukin 1 alpha antibody Interleukin 1 alpha precursor antibody Interleukin-1 alpha antibody Interleukin1 alpha antibody LAF antibody LEM antibody Preinterleukin 1 alpha antibody Pro interleukin 1 alpha antibody Pro interleukin 1 alpha antibody Prointerleukin 1 alpha antibody
Uniprot ID :
P01582
more info or order :
company information

Boster Immunoleader
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
www.bosterbio.com925.485.4527
headquarters: USA
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