Anti-IGF1 Antibody | Boster Immunoleader PA1374 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-IGF1 Antibody

catalog :

PA1374

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

publications citing this reagent :

Georgy G, Nassar N, Mansour H, Abdallah D. Cerebrolysin Ameloriates Cognitive Deficits in Type III Diabetic Rats. PLoS ONE. 2013;8:e64847 pubmed
Zhang H, Leng P, Wang Y, Zhang J. Treating human meniscal fibrochondrocytes with hIGF-1 gene by liposome. Clin Orthop Relat Res. 2009;467:3175-82 pubmed publisher

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-IGF1 Antibody

Catalog Number :

PA1374

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Insulin-like growth factor I(IGF1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human IGF1(80-96 aa GSSSRRAPQTGIVDECC), different from the mouse and rat sequences by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

Insulin-like growth factor 1(IGF-1) also known as somatomedin C or mechano growth factor is a protein that in humans is encoded by the IGF1 gene. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons.Justice et al.(1990) placed the mouse IGF1 gene on chromosome 10.

Reference :

1. Höppener JW, de Pagter-Holthuizen P, Geurts van Kessel AH, Jansen M, Kittur SD, Antonarakis SE, Lips CJ, Sussenbach JS (1985). "The human gene encoding insulin-like growth factor I is located on chromosome 12". Hum. Genet. 69 (2): 157–60. 2. Jansen M, van Schaik FM, Ricker AT, Bullock B, Woods DE, Gabbay KH, Nussbaum AL,Sussenbach JS, Van den Brande JL (1983). "Sequence of cDNA encoding human insulin-like growth factor I precursor". Nature 306 (5943): 609–11.

Gene Name :

IGF1

Protein Name :

Insulin-like growth factor I(IGF-I)

Gene Full Name :

insulin-like growth factor 1(somatomedin C)

Synonyms :

IBP1 antibody IGF 1 antibody IGF I antibody IGF IA antibody IGF IB antibody IGF-I antibody Igf1 antibody IGF1_HUMAN antibody IGFI antibody IGFIA antibody Insulin like growth factor 1(somatomedin C) antibody Insulin like growth factor 1 antibody Insulin like growth factor IA antibody Insulin like growth factor IB antibody Insulin-like growth factor I antibody Mechano growth factor antibody MGF antibody OTTHUMP00000195080 antibody OTTHUMP00000195081 antibody OTTHUMP00000195082 antibody OTTHUMP00000195083 antibody OTTHUMP00000195084 antibody Somatomedia C antibody Somatomedin C antibody Somatomedin-C antibody

Uniprot ID :

P05019

more info or order :

Boster Immunoleader product webpage