Anti-Cystatin C Antibody | Boster Immunoleader PA1369 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Cystatin C Antibody

catalog :

PA1369

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Cystatin C Antibody

Catalog Number :

PA1369

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Cystatin-C(CST3) detection. Tested with WB, IHC-P, ICC in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

WB,IHC-P,ICC

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human

Immunocytochemistry :

Concentration: 0.5-1μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human Cystatin C(45-63aa EEEGVRRALDFAVGEYNKA).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P) and ICC.

Background :

Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. By human-rodent somatic cell hybridizations, Abrahamson et al.(1989) mapped the human CST3 to chromosome 20. Cystatin C was originally described as a constituent of normal cerebrospinal fluid(CSF) and of urine from patients with renal failure(Grubb and Lofberg, 1982). It is present in a number of neuroendocrine cells and its concentration in the CSF was reported to be 5.5 times that in plasma of healthy adults(Lofberg and Grubb, 1979; Lofberg et al., 1981; Lofberg et al., 1983). Grubb and Lofberg(1982) detected the protein in human pituitary gland, and suggested that it is part of the gastroenteropancreatic neuroendocrine system.

Reference :

1. "Alzforum: AlzGene

Gene Name :

CST3

Protein Name :

Cystatin-C

Gene Full Name :

cystatin C

Synonyms :

AD 8 antibody AD8 antibody Amyloid angiopathy and cerebral hemorrhage antibody ARMD11 antibody bA218C14.4(cystatin C) antibody bA218C14.4 antibody Cst 3 antibody Cst3 antibody CST3 protein antibody Cystatin 3 antibody Cystatin-3 antibody Cystatin-C antibody Cystatin3 antibody CystatinC antibody CYTC_HUMAN antibody Gamma trace antibody Gamma-trace antibody HCCAA antibody MGC117328 antibody Neuroendocrine basic polypeptide antibody Post gamma globulin antibody Post-gamma-globulin antibody

Uniprot ID :

P01034

more info or order :

Boster Immunoleader product webpage