Boster Immunoleader

antibody

Anti-CDC42 Antibody

PA1366

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse, rat

western blot, immunohistochemistry - paraffin section

Anti-CDC42 Antibody

PA1366

Polyclonal

Rabbit IgG polyclonal antibody for Cell division control protein 42 homolog(CDC42) detection. Tested with WB, IHC-P in Human;Bovin;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, bovine, mouse, rat

WB,IHC-P

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Bovine, Mouse, Rat

Concentration: 0.5-1μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence in the middle region of human CDC42(121-138aa DDPSTIEKLAKNKQKPIT), identical to the related mouse and rat sequences.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Cell division control protein 42 homolog also known as CDC42 is a protein involved in regulation of the cell cycle. In humans, CDC42 is encoded by the CDC42 gene. CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein(N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.

1. Shinjo K, Koland JG, Hart MJ, Narasimhan V, Johnson DI, Evans T, Cerione RA (December 1990). 2. Munemitsu S, Innis MA, Clark R, McCormick F, Ullrich A, Polakis P (November 1990).

CDC42

Cell division control protein 42 homolog(Cdc42 homolog)

cell division cycle 42(GTP binding protein, 25kDa)

CDC 42 antibody CDC42 antibody CDC42_HUMAN antibody CDC42Hs antibody Cell division control protein 42 homolog antibody Cell division cycle 42(GTP binding protein 25kDa) antibody Cell division cycle 42 antibody Cell division cycle 42 isoform 1 antibody Cell division cycle 42 isoform 2 antibody dJ224A6.1.1(cell division cycle 42(GTP-binding protein, 25kD)) antibody dJ224A6.1.1 antibody dJ224A6.1.2(cell division cycle 42(GTP-binding protein, 25kD)) antibody dJ224A6.1.2 antibody G25K antibody G25K GTP binding protein antibody G25K GTP-binding protein antibody Growth regulating protein antibody GTP binding protein 25kD antibody GTP binding protein 25kDa antibody Small GTP binding protein CDC42 antibody

P60953