Anti-TNF beta Antibody | Boster Immunoleader PA1361-1 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-TNF beta Antibody

catalog :

PA1361-1

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-TNF beta Antibody

Catalog Number :

PA1361-1

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Lymphotoxin-alpha(LTA) detection. Tested with WB in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human TNF beta(45-59aa AQTARQHPKMHLAHS).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Lymphotoxin (previously known as tumor necrosis factor-beta) is a lymphokine cytokine.It is a protein that is produced by Th1 type T-cells and induces vascular endothelial cells to change their surface adhesion molecules to allow phagocytic cells to bind to them. Lymphotoxin is homologous to Tumor Necrosis Factor beta, but secreted by T-cells. It is paracrine due to the small amounts produced. The effects are similar to TNF-alpha, but TNF-beta is also important for the development of lymphoid organs. Nedwin et al. (1985) found that TNFA and TNFB are closely linked on chromosome 6. Study of hybrid cells made with rearranged human chromosome 6 showed that both TNFA and TNFB map to the 6p23-q12 segment.

Reference :

1. Parham, Peter (2005). "Chapter 6: T-cell mediated immunity". The immune system (2nd ed.). New York: Garland Science. p. 172.

Gene Name :

LTA

Protein Name :

Lymphotoxin-alpha(LT-alpha)

Gene Full Name :

lymphotoxin alpha(TNF superfamily, member 1)

Synonyms :

LTalpha antibody DIF antibody LT alpha antibody LT antibody LT-alpha antibody LTA antibody LTalpha antibody Lymphotoxin alpha(TNF superfamily, member 1) antibody Lymphotoxin alpha antibody Lymphotoxin-alpha antibody TNF B antibody TNF superfamily member 1 antibody TNF-beta antibody TNFB antibody TNFB_HUMAN antibody TNFbeta antibody TNFSF1 antibody Tumor necrosis factor beta antibody Tumor necrosis factor ligand superfamily member 1 antibody

Uniprot ID :

P01374

more info or order :

Boster Immunoleader product webpage