Anti-MMP9 Antibody | Boster Immunoleader PA1357 product information

product summary

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company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-MMP9 Antibody

catalog :

PA1357

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

publications citing this reagent :

Jia Z, Tian H, Kang K, Miao H, Liu K, Jiang S, et al. Expression of the tissue inhibitor of metalloproteinase-3 by transplanted VSMCs modifies heart structure and function after myocardial infarction. Transpl Immunol. 2014;30:149-58 pubmed publisher
Zhou Y, Tan X, Kuang W, Liu L, Wan L. Erythromycin ameliorates cigarette-smoke-induced emphysema and inflammation in rats. Transl Res. 2012;159:464-72 pubmed publisher
Cheng G, Wei L, Xiurong W, Xiangzhen L, Shiguang Z, Songbin F. IL-17 stimulates migration of carotid artery vascular smooth muscle cells in an MMP-9 dependent manner via p38 MAPK and ERK1/2-dependent NF-kappaB and AP-1 activation. Cell Mol Neurobiol. 2009;29:1161-8 pubmed publisher
Fang Z, Lin R, Yuan B, Liu Y, Zhang H. Tanshinone IIA inhibits atherosclerotic plaque formation by down-regulating MMP-2 and MMP-9 expression in rabbits fed a high-fat diet. Life Sci. 2007;81:1339-45 pubmed

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product information

Availability :

info changed 20150427

Product Name :

Anti-MMP9 Antibody

Catalog Number :

PA1357

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Matrix metalloproteinase-9(MMP9) detection. Tested with WB in Human;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat

Notes :

WB: The detection limit for MMP9 is approximately 0.5ng/lane under reducing conditions. Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human MMP9(689-705aa NQVDQVGYVTYDILQCP), different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Matrix metallopeptidase 9(MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B(GELB), is an enzyme that in humans is encoded by the MMP9 gene. Proteins of the matrix metalloproteinase(MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Reference :

1. Template:, 92kDa type IV collagenase) 2. Yuichiro Hirose et al. (May 2008). "A Functional Polymorphism in THBS2 that Affects Alternative Splicing and MMP Binding Is Associated with Lumbar-Disc Herniation".

Gene Name :

MMP9

Protein Name :

Matrix metalloproteinase-9(MMP-9)

Gene Full Name :

matrix metallopeptidase 9(gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)

Synonyms :

82 kDa matrix metalloproteinase-9 antibody 92 kDa gelatinase antibody 92 kDa type IV collagenase antibody CLG 4B antibody CLG4B antibody Collagenase Type 4 beta antibody Collagenase type IV 92 KD antibody EC 3.4.24.35 antibody Gelatinase 92 KD antibody Gelatinase B antibody Gelatinase beta antibody GelatinaseB antibody GELB antibody Macrophage gelatinase antibody MANDP2 antibody Matrix metallopeptidase 9(gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) antibody Matrix Metalloproteinase 9 antibody MMP 9 antibody MMP-9 antibody MMP9 antibody MMP9_HUMAN antibody Type V collagenase antibody

Uniprot ID :

P14780

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