Anti-IL-8 Antibody | Boster Immunoleader PA1353 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-IL-8 Antibody

catalog :

PA1353

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-IL-8 Antibody

Catalog Number :

PA1353

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Interleukin-8(IL8) detection. Tested with WB, IHC-P in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human IL8(77-95aa CLDPKENWVQRVVEKFLKR).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

Interleukin-8(IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is encoded by the IL8 gene. Interleukin-8(IL8) is a member of the CXC chemokine family(Hull et al., 2001). IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. The genes for IL8 have been co-localized on a 335-kb genomic fragment.

Reference :

1. Wolff B, Burns AR, Middleton J, Rot A (November 1998). "Endothelial cell "memory" of inflammatory stimulation: human venular endothelial cells store interleukin 8 in Weibel-Palade bodies". 2. Utgaard JO, Jahnsen FL, Bakka A, Brandtzaeg P, Haraldsen G (November 1998). "Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells". 3. Modi WS, Dean M, Seuanez HN, Mukaida N, Matsushima K, O'Brien SJ (January 1990). "Monocyte-derived neutrophil chemotactic factor (MDNCF/IL-8) resides in a gene cluster along with several other members of the platelet factor 4 gene superfamily". 4. "Entrez Gene: IL8 interleukin 8". 5. Köhidai L, Csaba G (July 1998). "Chemotaxis and chemotactic selection induced with cytokines (IL-8, RANTES and TNF-alpha) in the unicellular Tetrahymena pyriformis". 6. O'Donovan, N., Galvin, M., Morgan, J. G. Physical mapping of the CXC chemokine locus on human chromosome 4. Cytogenet.

Gene Name :

IL8

Protein Name :

Interleukin-8(IL-8)

Gene Full Name :

interleukin 8

Synonyms :

(Ala-IL-8)77 antibody (Ser-IL-8)72 antibody 3 10C antibody 310C antibody AMCF 1 antibody AMCF1 antibody b ENAP antibody Bbeta thromboglobulin like protein antibody Beta thromboglobulin like protein antibody C-X-C motif chemokine 8 antibody CXC chemokine ligand 8 antibody CXCL 8 antibody CXCL8 antibody Emoctakin antibody GCP 1 antibody GCP-1 antibody GCP/IL-8 protein I antibody GCP/IL-8 protein II antibody GCP/IL-8 protein III antibody GCP/IL-8 protein IV antibody GCP/IL-8 protein V antibody GCP/IL-8 protein VI antibody GCP1 antibody Granulocyte chemotactic protein 1 antibody IL 8 antibody IL-8 antibody IL-8(1-77) antibody IL-8(9-77) antibody IL8 antibody IL8/NAP1 form I antibody IL8/NAP1 form II antibody IL8/NAP1 form III antibody IL8/NAP1 form IV antibody IL8/NAP1 form V antibody IL8/NAP1 form VI antibody IL8_HUMAN antibody Inteleukin 8 antibody Interleukin8 antibody K 60 antibody K60 antibody LECT antibody LUCT antibody Lymphocyte derived neutrophil activating factor antibody Lymphocyte-derived neutrophil-activating factor antibody LYNAP antibody MDNCF antibody MDNCF-b antibody MDNCF-c antibody MONAP antibody Monocyte derived neutrophil activating peptide antibody Monocyte derived neutrophil activating protein antibody Monocyte derived neutrophil chemotactic factor antibody Monocyte-derived neutrophil chemotactic factor antibody Monocyte-derived neutrophil-activating peptide antibody NAF antibody NAP 1 antibody NAP-1 antibody NAP1 antibody Neutrophil activating factor antibody Neutrophil activating peptide 1 antibody Neutrophil activating protein 1 antibody Neutrophil-activating factor antibody Neutrophil-activating protein 1 antibody Protein 3 10C antibody Protein 3-10C antibody SCYB 8 antibody SCYB8 antibody Small inducible cytokine subfamily B member 8 antibody T cell chemotactic factor antibody T-cell chemotactic factor antibody TSG 1 antibody TSG1 antibody

Uniprot ID :

P10145

more info or order :

Boster Immunoleader product webpage