Anti-HDAC2 Antibody | Boster Immunoleader PA1350 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-HDAC2 Antibody

catalog :

PA1350

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-HDAC2 Antibody

Catalog Number :

PA1350

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Histone deacetylase 2(HDAC2) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human HDAC2(464-478aa EDKSKDNSGEKTDTK), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Histone deacetylase 2 is an enzyme that in humans is encoded by the HDAC2 gene. This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones(H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Betz et al.(1998) performed PCR using HDAC2-specific primers to screen a somatic cell hybrid mapping panel. They mapped the HDAC2 gene to human chromosome 6q21, a region of the genome altered in some cancers, including retinoblastoma.

Reference :

1. Betz R, Gray SG, Ekstrom C, Larsson C, Ekstrom TJ (Dec 1998). "Human histone deacetylase 2, HDAC2 (Human RPD3), is localized to 6q21 by radiation hybrid mapping".

Gene Name :

HDAC2

Protein Name :

Histone deacetylase 2(HD2)

Gene Full Name :

histone deacetylase 2

Synonyms :

D10Wsu179e antibody HD 2 antibody HD2 antibody HDAC 2 antibody Hdac2 antibody HDAC2_HUMAN antibody Histone deacetylase 2(HD2) antibody histone deacetylase 2 antibody OTTHUMP00000017046 antibody OTTHUMP00000227077 antibody OTTHUMP00000227078 antibody RPD3 antibody transcriptional regulator homolog RPD3 antibody YAF1 antibody YY1 associated factor 1 antibody YY1 transcription factor binding protein antibody Yy1bp antibody

Uniprot ID :

Q92769

more info or order :

Boster Immunoleader product webpage