Anti-HDAC1 Antibody | Boster Immunoleader PA1349 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-HDAC1 Antibody

catalog :

PA1349

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-HDAC1 Antibody

Catalog Number :

PA1349

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Histone deacetylase 1(HDAC1) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC1(1-14aa MAQTQGTRRKVCYY), identical to the related mouse and rat sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Histone deacetylase 1 is an enzyme that in humans is encoded by the HDAC1 gene. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. Furukawa et al.(1996) mapped RPD3L1 to 1p34.1 by fluorescence in situ hybridization.

Reference :

1. Taunton J, Hassig CA, Schreiber SL (May 1996). "A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p".

Gene Name :

HDAC1

Protein Name :

Histone deacetylase 1(HD1)

Gene Full Name :

histone deacetylase 1

Synonyms :

DKFZp686H12203 antibody GON 10 antibody HD 1 antibody HD1 antibody HDAC 1 antibody HDAC1 antibody hdac1: histone deacetylase 1 antibody HDAC1_HUMAN antibody Histone deacetylase 1(HD1) antibody Histone deacetylase 1 antibody Reduced potassium dependency yeast homolog like 1 antibody RPD3(reduced potassium dependency yeast homolog) like 1 antibody RPD3(reduced potassium dependency) antibody RPD3 antibody RPD3L1 antibody

Uniprot ID :

Q13547

more info or order :

Boster Immunoleader product webpage