Anti-FAF1 Antibody | Boster Immunoleader PA1337 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-FAF1 Antibody

catalog :

PA1337

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-FAF1 Antibody

Catalog Number :

PA1337

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for FAS-associated factor 1(FAF1) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human FAF1(1-22aa MASNMDREMILADFQACTGIEN), identical to the related mouse and rat sequences.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Fas-associated factor-1(FAF1) is a Fas-binding pro-apoptotic protein that is a component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 is involved in negative regulation of NF-kappaB activation. In addition to the previously known function as a component of the Fas death-inducing signaling complex, i.e. NF-kappaB activity suppressor by cytoplasmic retention of NF-kappaB p65 via physical interaction. hFAF1 was expressed abundantly in testis, skeletal muscle, and heart as 2.8 kb mRNA. Polyclonal antibody against hFAF1 detected 74 kD protein, a deduced protein size from the ORF and 40 kD protein in some cell lines.

Reference :

1. J Biol Chem. 2004 Jan 23;279(4):2544-9. Epub 2003 Nov 4.Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB.Research Center for Biomedicinal Resources and the Division of Life Science, PaiChai University, Daejeon 302-735, Korea. 2. 1 Ryu, S. W., Chae, S. K., Lee, K. J., Kim, E. Identification and characterization of human Fas associated factor 1, hFAF1. Biochem. Biophys. Res. Commun. 262: 388-394, 1999.

Gene Name :

FAF1

Protein Name :

FAS-associated factor 1(hFAF1)

Gene Full Name :

Fas(TNFRSF6) associated factor 1

Synonyms :

CGI 03 antibody FAF1 antibody FAF1 protein antibody FAF1_HUMAN antibody Fas(TNFRSF6) associated factor 1 antibody FAS associated factor 1 antibody Fas associated protein factor 1 antibody FAS-associated factor 1 antibody FLJ37524 antibody hFAF1 antibody HFAF1s antibody Protein FAF1 antibody TNFRSF6 associated factor 1 antibody UBX domain protein 3A antibody UBX domain-containing protein 12 antibody UBX domain-containing protein 3A antibody UBXD12 antibody UBXN3A antibody

Uniprot ID :

Q9UNN5

more info or order :

Boster Immunoleader product webpage