Anti-Bcl-XS Antibody | Boster Immunoleader PA1232 product information

product summary

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company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Bcl-XS Antibody

catalog :

PA1232

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Availability :

info changed 20150604

Product Name :

Anti-Bcl-XS Antibody

Catalog Number :

PA1232

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Bcl-2-like protein 1(BCL2L1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human Bcl-XS(120-130aa YQSFEQDTFVE), different from the related rat and mouse sequences by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

Bcl-xS is the second mRNA species of Bcl-x protein, which encodes a protein that inhibits the ability of bcl-2 to enhance the survival of growth factor-deprived cells. In vivo, bcl-xS mRNA is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. Apoptosis was associated with increased protein expression of Bcl-X/S, an early marker of apoptosis, and release of cytochrome c into the cytosol of infected HB cells.

Reference :

1. Boise, L. H.; Gonzalez-Garcia, M.; Postema, C. E.; Ding, L.; Lindsten, T.; Turka, L. A.; Mao, X.; Nunez, G.; Thompson, C. B. : Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74: 597-608, 1993. 2. Glushakova LG, Lisankie MJ, Eruslanov EB, Ojano-Dirain C, Zolotukhin I, Liu C, Srivastava A, Stacpoole PW. AAV3-mediated transfer and expression of the pyruvate dehydrogenase E1 alpha subunit gene causes metabolic remodeling and apoptosis of human liver cancer cells. Mol Genet Metab. 2009 Jun 23.

Gene Name :

BCL2L1

Protein Name :

Bcl-2-like protein 1(Bcl2-L-1)

Gene Full Name :

BCL2-like 1

Synonyms :

Apoptosis regulator Bcl X antibody Apoptosis regulator Bcl-X antibody Apoptosis regulator BclX antibody B cell lymphoma 2 like antibody B2CL1_HUMAN antibody Bcl 2 like 1 protein antibody Bcl X antibody Bcl xL antibody BCL XL/S antibody Bcl xS antibody Bcl-2-like protein 1 antibody Bcl2 Like 1 antibody Bcl2 related gene antibody Bcl2-L-1 antibody Bcl2l1 antibody BCLX antibody BclXL antibody BclXs antibody DKFZp781P2092 antibody PPP1R52 antibody Protein phosphatase 1 regulatory subunit 52 antibody

Uniprot ID :

Q07817

more info or order :

Boster Immunoleader product webpage