Anti-NTE Antibody | Boster Immunoleader PA1226 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-NTE Antibody

catalog :

PA1226

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

zebrafish

application :

western blot, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

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product information

Availability :

info changed 20150507

Product Name :

Anti-NTE Antibody

Catalog Number :

PA1226

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for patatin-like phospholipase domain containing 6(PNPLA6) detection. Tested with WB, IHC-P, IHC-F in Zebrafish.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Liquid

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: Zebrafish

Applications :

WB,IHC-P,IHC-F

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Zebrafish

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Zebrafish

Immunohistochemistry(Frozen Section) :

Concentration: 0.5-1μg/ml; Tested Species: Zebrafish

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of fish NTE(1317-1342aa DEDKTVRQRKNVSRDPNADFSGVSDC ).

Contents :

Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4.

Purification :

Immunogen affinity purified.

Storage :

At -20˚C for one year, at 4˚C for one month. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P) and IHC(F).

Background :

Patatin-like phospholipase domain containing 6(PNPLA6), also known as Neuropathy target esterase(NTE), is a human gene. Neuropathy target esterase(NTE) is involved in neural development and is the target for neurodegeneration induced by selected organophosphorus pesticides and chemical warfare agents. The genetic or chemical reduction of Nte activity results in a neurological phenotype of hyperactivity in mammals and indicate that EOPF toxicity occurs directly through inhibition of Nte without the requirement for Nte gain of function or aging.

Reference :

1. Winrow, C. J.; Hemming, M. L.; Allen, D. M.; Quistad, G. B.; Casida, J. E.; Barlow, C. : Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity. Nature Genet. 33: 477-486, 2003.

Gene Name :

PNPLA6

Protein Name :

patatin-like phospholipase domain containing 6

Gene Full Name :

patatin-like phospholipase domain containing 6

Synonyms :

EC 3.1.1.5 antibody Neuropathy target esterase antibody NTEMND antibody Patatin like phospholipase domain containing 6 antibody Patatin like phospholipase domain containing protein 6 antibody Patatin-like phospholipase domain-containing protein 6 antibody PLPL6_HUMAN antibody Pnpla6 antibody SPG39 antibody sws antibody

Uniprot ID :

F1R844

more info or order :

Boster Immunoleader product webpage