Anti-Notch1 Antibody | Boster Immunoleader PA1215 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Notch1 Antibody

catalog :

PA1215

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Notch1 Antibody

Catalog Number :

PA1215

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Neurogenic locus notch homolog protein 1(NOTCH1) detection. Tested with WB in Human.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence in the middle region of human Notch1(2487-2506aa QHSYSSPVDNTPSHQLQVPE).

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Notch proteins are single-pass transmembrane receptors that regulate cell fate decisions during development. The Notch family includes 4 receptors, NOTCH1, NOTCH2, NOTCH3, and NOTCH4, whose ligands include JAG1, JAG2, DLL1), DLL3, and DLL4. Notch homolog 1, translocation-associated(NOTCH1), is a human gene encoding a single-pass transmembrane receptor. It functions as a receptor for membrane bound ligands, and may play multiple roles during development. NOTCH1 may normally coordinates the process of somitogenesis, and the activated Notch 1 and Notch 3 promote differentiation of progenitor cells into astroglia.

Reference :

1. Conlon, R. A.; Reaume, A. G.; Rossant, J. : Notch1 is required for the coordinate segmentation of somites. Development 121: 1533-1545, 1995. 2. Tanigaki K, Nogaki F, Takahashi J, Tashiro K, Kurooka H, Honjo T (January 2001). "Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate". Neuron 29 (1): 45–55.

Gene Name :

NOTCH1

Protein Name :

Neurogenic locus notch homolog protein 1(Notch 1/hN1)

Gene Full Name :

notch 1

Synonyms :

9930111A19RIK antibody hN1 antibody Lin-12 antibody LIN12 antibody MIS6 antibody Motch A antibody mT14 antibody Neurogenic locus notch homolog protein 1 antibody Neurogenic locus notch protein homolog antibody NICD antibody NOTC1_HUMAN antibody Notch 1 antibody Notch 1 extracellular truncation antibody Notch 1 intracellular domain antibody NOTCH antibody Notch gene homolog 1(Drosophila) antibody Notch homolog 1 translocation associated(Drosophila) antibody Notch homolog 1, translocation-associated(Drosophila) antibody NOTCH, Drosophila, homolog of, 1 antibody notch1 antibody p300 antibody TAN 1 antibody TAN1 antibody TAN1 antibody Translocation Associated Notch Homolog antibody Translocation associated notch protein TAN 1 antibody Translocation-associated notch protein TAN-1 antibody xotch antibody

Uniprot ID :

P46531

more info or order :

Boster Immunoleader product webpage