Boster Immunoleader

antibody

Anti-CCR6 Antibody

PA1201

100 ug/vial

200 USD

polyclonal

rabbit

human, mouse, rat

Anti-CCR6 Antibody

PA1201

Polyclonal

Rabbit IgG polyclonal antibody for C-C chemokine receptor type 6(CCR6) detection. Tested with WB in Human;Mouse;Rat.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human, rat Predicted to work with: mouse

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence at the C-terminus of human CCR6(358-374aa RQTSETADNDNASSFTM), different from the related rat and mouse sequences by two amino acids.

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.

1. Zaballos, A.; Varona, R.; Gutierrez, J.; Lind, P.; Marquez, G. : Molecular cloning and RNA expression of two new human chemokine receptor-like genes. Biochem. Biophys. Res. Commun. 227: 846-853, 1996. 2. Liao, F.; Lee, H.-H.; Farber, J. M. : Cloning of STRL22, a new human gene encoding a G-Protein-coupled receptor related to chemokine receptors and located on chromosome 6q27. Genomics 40: 175-180, 1997. 3. Homey, B.; Dieu-Nosjean, M.-C.; Wiesenborn, A.; Massacrier, C.; Pin, J.-J.; Oldham, E.; Catron, D.; Buchanan, M. E.; Muller, A.; de Waal Malefyt, R.; Deng, G.; Orozco, R.; Ruzicka, T.; Lehmann, P.; Lebecque, S.; Caux, C.; Zlotnik, A. : Up-regulation of macrophage inflammatory protein-3-alpha/CCL20 and CC chemokine receptor 6 in psoriasis. J. Immun. 164: 6621-6632, 2000.

CCR6

C-C chemokine receptor type 6(C-C CKR-6/CC-CKR-6/CCR-6)

chemokine(C-C motif) receptor 6

BN 1 antibody BN1 antibody C C chemokine receptor type 6 antibody C C CKR 6 antibody C-C chemokine receptor type 6 antibody C-C CKR-6 antibody CC chemokine receptor type 6 antibody CC CKR 6 antibody CC R6 antibody CC-CKR-6 antibody CCCKR6 antibody CCR 6 antibody CCR-6 antibody Ccr6 antibody CCR6_HUMAN antibody CD 196 antibody CD196 antibody CD196 antigen antibody Chemokine(C C motif) receptor 6 antibody Chemokine(C C) receptor 6 antibody Chemokine(CC motif) receptor 6 antibody Chemokine(CC) receptor 6 antibody Chemokine receptor 6 antibody Chemokine receptor like 3 antibody Chemokine receptor-like 3 antibody CKR 6 antibody CKR L3 antibody CKR-L3 antibody CKR6 antibody CKRL3 antibody CMKBR6 antibody CMKBR6 antibody DCR 2 antibody DCR2 antibody DRY 6 antibody DRY6 antibody G protein coupled receptor 29 antibody G-protein coupled receptor 29 antibody GPR 29 antibody GPR CY4 antibody GPR-CY4 antibody GPR29 antibody GPRCY 4 antibody GPRCY4 antibody LARC receptor antibody Seven transmembrane receptor lymphocyte 22 antibody STRL 22 antibody STRL22 antibody

P51684