Anti-gamma Catenin Antibody | Boster Immunoleader PA1117 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-gamma Catenin Antibody

catalog :

PA1117

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-gamma Catenin Antibody

Catalog Number :

PA1117

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Junction plakoglobin(JUP) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

WB,IHC-P

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Immunohistochemistry(Paraffin-embedded S ... :

Concentration: 0.5-1μg/ml; Tested Species: Rat; Predicted Species: Human, Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human gamma Catenin(8-22aa EQPIKVTEWQQTYTY), identical to the related mouse and rat sequence.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB, supported by SA1022 in IHC(P).

Background :

Cateningamma, also known as junction plakoglobin(JUP) or plakoglobin(PKGB). Plakoglobin is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. Cateninbeta and cateningamma(plakoglobin), vertebrate homologs of Drosophila armadillo, function in cell adhesion and the Wnt signaling pathway. Cateningamma may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.

Reference :

1. Kolligs, F. T.; Kolligs, B.; Hajra, K. M.; Hu, G.; Tani, M.; Cho, K. R.; Fearon, E. R. : Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. Genes Dev. 14: 1319-1331, 2000.

Gene Name :

JUP

Protein Name :

Junction plakoglobin

Gene Full Name :

junction plakoglobin

Synonyms :

ARVD 12 antibody ARVD12 antibody Catenin(cadherin associated protein) gamma 80kDa antibody Catenin(cadherin associated protein), gamma 80kDa antibody catenin(cadherin-associated protein) gamma(80kD) antibody Catenin gamma 80kDa antibody Catenin gamma antibody CTNNG antibody Desmoplakin 3 antibody Desmoplakin III antibody Desmoplakin-3 antibody Desmoplakin3 antibody DesmoplakinIII antibody DP 3 antibody DP III antibody DP3 antibody DPIII antibody Gamma catenin antibody Junction plakoglobin antibody JUP antibody OTTHUMP00000164732 antibody OTTHUMP00000164735 antibody OTTHUMP00000164738 antibody PDGB antibody PKGB antibody PLAK_HUMAN antibody PLAKOGLOBIN antibody

Uniprot ID :

P14923

more info or order :

Boster Immunoleader product webpage