Anti-NMDAR2B Antibody | Boster Immunoleader PA1059 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-NMDAR2B Antibody

catalog :

PA1059

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

more info or order :

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product information

Product Name :

Anti-NMDAR2B Antibody

Catalog Number :

PA1059

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Glutamate receptor ionotropic, NMDA 2B(GRIN2B) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: mouse, rat Predicted to work with: human

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse, Rat; Predicted Species: Human

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the C-terminus of human NMDAR2B(1131-1146aa, DFYLDQFRTKENSPHW), identical to the related mouse and rat sequence.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

The N-methyl-D-aspartate receptor 2B, also names as GRIN2B. The sequence of the predicted 1,484-amino acid human protein is 98% and 96% identical to the sequences of the rat and mouse Nmdar2b proteins, respectively. Nmdar2B gene is located on mouse chromosome 6 between Rho and Ly49 centromerically and Glb telomerically. Mapping of the human NMDAR2B receptor subunit gene(GRIN2B) to chromosome 12p12 overexpression of NMDA receptor 2B(NR2B) in the forebrains of transgenic mice leads to enhanced activation of NMDA receptors, facilitating synaptic potentiation in response to stimulation at 10-100 Hz.

Reference :

1. Mandich, P.; Schito, A. M.; Bellone, E.; Antonacci, R.; Finelli, P.; Rocchi, M.; Ajmar, F. : Mapping of the human NMDAR2B receptor subunit gene (GRIN2B) to chromosome 12p12. Genomics 22: 216-218, 1994. 2. Tang, Y.-P.; Shimizu, E.; Dube, G. R.; Rampon, C.; Kerchner, G. A.; Zhuo, M.; Liu, G.; Tsien, J. Z. : Genetic enhancement of learning and memory in mice. Nature 401: 63-69, 1999.

Gene Name :

GRIN2B

Protein Name :

Glutamate receptor ionotropic, NMDA 2B

Gene Full Name :

glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Synonyms :

AW490526 antibody Glutamate[NMDA] receptor subunit epsilon 2 antibody Glutamate[NMDA] receptor subunit epsilon-2 antibody Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody Glutamate receptor ionotropic NMDA2B antibody Glutamate receptor subunit epsilon 2 antibody Glutamate receptor, ionotropic, NMDA2B(epsilon 2) antibody GRIN 2B antibody GRIN2B antibody hNR 3 antibody hNR3 antibody MGC142178 antibody MGC142180 antibody N methyl D asparate receptor channel subunit epsilon 2 antibody N METHYL D ASPARTATE RECEPTOR CHANNEL SUBUNIT EPSILON 2 antibody N methyl D aspartate receptor subtype 2B antibody N methyl D aspartate receptor subunit 2B antibody N methyl D aspartate receptor subunit 3 antibody N-methyl D-aspartate receptor subtype 2B antibody N-methyl-D-aspartate receptor subunit 3 antibody NMDA NR2B antibody NMDA R2B antibody Nmdar2b antibody NMDE2 antibody NMDE2_HUMAN antibody NME2 antibody NR2B antibody NR3 antibody

Uniprot ID :

Q13224

more info or order :

Boster Immunoleader product webpage