Anti-NGF Antibody | Boster Immunoleader PA1056 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-NGF Antibody

catalog :

PA1056

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

publications citing this reagent :

Wang Y, Wang K, Chao R, Li J, Zhou L, Ma J, et al. Neuroprotective effect of vaccination with autoantigen-pulsed dendritic cells after spinal cord injury. J Surg Res. 2012;176:281-92 pubmed publisher
Cao L, Zhu Y, Su Z, Lv B, Huang Z, Mu L, et al. Olfactory ensheathing cells promote migration of Schwann cells by secreted nerve growth factor. Glia. 2007;55:897-904 pubmed

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-NGF Antibody

Catalog Number :

PA1056

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Beta-nerve growth factor(NGF) detection. Tested with WB in Human;Mouse;Rat.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: human, rat Predicted to work with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Human, Rat; Predicted Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of human NGF(162-173aa EVNINNSVFKQY), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.

Contents :

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification :

Immunogen affinity purified.

Reconstitution :

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

Nerve growth factor is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. The nucleotide sequence of human and mouse beta-NGF are very similar. The beta-subunits of nerve growth factor(NGFB) have been assigned to mouse chromosome 3 and human chromosome 1p22. The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1. A mutation in the nerve growth factor beta gene(NGFB) causes loss of pain perception.

Reference :

1. Dracopoli, N. C.; Rose, E.; Whitfield, G. K.; Guidon, P. T.; Bale, S. J.; Chance, P. A.; Kourides, I. A.; Housman, D. E. : Two thyroid hormone regulated genes, the beta-subunits of nerve growth factor (NGFB) and thyroid stimulating hormone (TSHB), are located less than 310 kb apart in both human and mouse genomes. Genomics 3: 161-167, 1988. 2. Francke, U.; de Martinville, B.; Coussens, L.; Ullrich, A. : The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1. Science 222: 1248-1251, 1983 3. Einarsdottir, E.; Carlsson, A.; Minde, J.; Toolanen, G.; Svensson, O.; Solders, G.; Holmgren, G.; Holmberg, D.; Holmberg, M. : A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception. Hum. Molec. Genet. 13: 799-805, 2004.

Gene Name :

NGF

Protein Name :

Beta-nerve growth factor(Beta-NGF)

Gene Full Name :

nerve growth factor(beta polypeptide)

Synonyms :

Beta nerve growth factor antibody Beta nerve growth factor precursor antibody Beta NGF antibody Beta-nerve growth factor antibody Beta-NGF antibody HSAN5 antibody MGC161426 antibody MGC161428 antibody Nerve growth factor beta antibody Nerve growth factor beta polypeptide antibody Nerve growth factor beta subunit antibody NGF antibody NGF B antibody NGF_HUMAN antibody NGFB antibody NID67 antibody

Uniprot ID :

P01138

more info or order :

Boster Immunoleader product webpage