Anti-CD40 Antibody | Boster Immunoleader PA1019 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-CD40 Antibody

catalog :

PA1019

quantity :

100 ug/vial

price :

200 USD

clonality :

polyclonal

host :

rabbit

reactivity :

mouse

application :

western blot

publications citing this reagent :

Peng Y, Cheng L, Zeng Q, Shi Y, Bao X, Mao X, et al. The role of RANTES as a crucial downstream cytokine in calcineurin-dependent VSMC apoptosis stimulated by INFgamma and CD40L. Cell Biol Int. 2010;34:447-53 pubmed publisher
Chen P, Chen R, Yang Y, Yu Y, Xie Y, Zou Y, et al. Coxsackievirus B3 infection promotes generation of myeloid dendritic cells from bone marrow and accumulation in the myocardium. Int Immunopharmacol. 2009;9:1304-12 pubmed publisher

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Boster Immunoleader product webpage

product information

Availability :

info changed 20150507

Product Name :

Anti-CD40 Antibody

Catalog Number :

PA1019

Clonality :

Polyclonal

Description short :

Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 5(CD40) detection. Tested with WB in Mouse.

Price :

200 USD

Ig type :

Rabbit IgG

Size :

100 ug/vial

Form :

Liquid

Specificity :

No cross reactivity with other proteins.

Reactivity :

Reacts with: mouse

Applications :

Western blot :

Concentration: 0.1-0.5μg/ml; Tested Species: Mouse

Notes :

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

A synthetic peptide corresponding to a sequence at the N-terminus of mouse CD40(22-36aa, QCVTCSDKQYLHDGQ).

Contents :

Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4.

Purification :

Immunogen affinity purified.

Storage :

At -20˚C for one year, at 4˚C for one month. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Background :

CD40 is a cell surface receptor that is expressed on the surface of all mature B cells and also expressed on monocytes, dendritic cells, and thymic epithelium. CD40 is a member of the tumor necrosis factor(TNF) receptor superfamily and is the receptor for CD40 ligand. CD40 ligand(CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40 predominantly on activated CD4+ T cells. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin.

Reference :

1. Clark, E. A. : CD40: a cytokine receptor in search of a ligand. Tissue Antigens 35: 33-36, 1990. 2. Harding, S. A.; Sarma, J.; Josephs, D. H.; Cruden, N. L.; Din, J. N.; Twomey, P. J.; Fox, K. A. A.; Newby, D. E. : Upregulation of the CD40/CD40 ligand dyad and platelet-monocyte aggregation in cigarette smokers. Circulation 109: 1926-1929, 2004. 3. Stamenkovic, I.; Clark, E. A.; Seed, B. : A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. EMBO J. 8: 1403-1410, 1989. 4. van Kooten, C.; Banchereau, J. : CD40-CD40 ligand. J. Leuko. Biol. 67: 2-17, 2000. 5. Kato, K.; Cantwell, M. J.; Sharma, S.; Kipps, T. J. : Gene transfer of CD40-ligand induces autologous immune recognition of chronic lymphocytic leukemia B cells. J. Clin. Invest. 101: 1133-1141, 1998.

Gene Name :

CD40

Protein Name :

Tumor necrosis factor receptor superfamily member 5

Gene Full Name :

CD40 molecule, TNF receptor superfamily member 5

Synonyms :

AI326936 antibody B cell associated molecule CD40 antibody B cell surface antigen CD40 antibody B cell-associated molecule antibody B-cell surface antigen CD40 antibody Bp50 antibody CD 40 antibody CD40 antibody CD40 antigen(TNF receptor superfamily member 5) antibody CD40 antigen antibody CD40 molecule antibody CD40 molecule, TNF receptor superfamily member 5 antibody CD40 protein antibody CD40 type II isoform antibody CD40L receptor antibody CDw40 antibody GP39 antibody HIGM1 antibody IGM antibody IMD3 antibody MGC9013 antibody Nerve growth factor receptor related B lymphocyte activation molecule antibody OTTHUMP00000031699 antibody OTTHUMP00000031700 antibody p50 antibody T-BAM antibody TBAM antibody TNF receptor superfamily member 5 antibody TNFRSF5 antibody TNR5_HUMAN antibody TRAP antibody Tumor necrosis factor receptor superfamily , member 5 antibody Tumor necrosis factor receptor superfamily member 5 antibody Tumor necrosis factor receptor superfamily member 5 precursor antibody Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a antibody

Uniprot ID :

P27512

more info or order :

Boster Immunoleader product webpage