Boster Immunoleader

antibody

Anti-CCR5 Antibody

PA1016-1

100 ug/vial

200 USD

polyclonal

rabbit

Anti-CCR5 Antibody

PA1016-1

Polyclonal

Rabbit IgG polyclonal antibody for C-C chemokine receptor type 5(CCR5) detection. Tested with WB in Human.

200 USD

Rabbit IgG

100 ug/vial

Lyophilized

No cross reactivity with other proteins.

Reacts with: human

WB

Concentration: 0.1-0.5μg/ml; Tested Species: Human

Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

A synthetic peptide corresponding to a sequence in the middle region of human CCR5(179-197aa SSHFPYSQYQFWKNFQTLK).

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Immunogen affinity purified.

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1002 in WB.

Human CC chemokine receptor 5(CCR5), which is 17.5 kb from the CMKBR2 gene, encodes a 352-amino acid protein with a calculated molecular mass of 40,600 Da. It is organized into four exons and two introns. Human CCR5 is a co-receptor for macrophage-tropic strains of human immunodeficiency virus(HIV)-1 and is expressed by bone-marrow-derived cells. CCR5 is expressed on neurons, astrocytes, and microglia in the central nervous system, and on epithelium, endothelium, vascular smooth muscle and fibroblasts in other tissues. Functionally, CCR5 mediates the activation of cells by the chemokines macrophage inflammatory protein-1alpha, macrophage inflammatory protein-1beta, and RANTES, and serves as a fusion cofactor for macrophage-tropic strains of human immunodeficiency virus type 1.

1. Samson M, Labbe O, Mollereau C, Vassart G, Parmentier M. Molecular cloning and functional expression of a new human CC-chemokine receptor gene. Biochemistry. 1996 Mar 19; 35(11):3362-7. 2. Rottman JB, Ganley KP, Williams K, Wu L, Mackay CR, Ringler DJ. Cellular localization of the chemokine receptor CCR5. Correlation to cellular targets of HIV-1 infection. Am J Pathol. 1997 Nov; 151(5):1341-51. 3. Mummidi S, Ahuja SS, McDaniel BL, Ahuja SK. The human CC chemokine receptor 5 (CCR5) gene. Multiple transcripts with 5'-end heterogeneity, dual promoter usage, and evidence for polymorphisms within the regulatory regions and noncoding exons. J Biol Chem. 1997 Dec 5; 272(49):30662-71.

CCR5

C-C chemokine receptor type 5

chemokine(C-C motif) receptor 5(gene/pseudogene)

AM4 7 antibody C C chemokine receptor type 5 antibody C C CKR 5 antibody C-C chemokine receptor type 5 antibody C-C CKR-5 antibody C-C motif chemokine receptor 5 A159A antibody CC Chemokine Receptor 5 antibody CC Chemokine Receptor Type 5 antibody CC CKR 5 antibody CC-CKR-5 antibody CCCKR 5 antibody CCCKR5 antibody CCR 5 antibody CCR-5 antibody CCR5 antibody CCR5 chemokine(C C motif) receptor 5 antibody CCR5_HUMAN antibody CD 195 antibody CD195 antibody CD195 Antigen antibody Chemokine C C motif receptor 5 antibody Chemokine receptor CCR5 antibody CHEMR13 antibody CKR 5 antibody CKR5 antibody CMKBR 5 antibody CMKBR5 antibody FLJ78003 antibody HIV 1 Fusion Coreceptor antibody HIV-1 fusion coreceptor antibody HIV1 fusion coreceptor antibody IDDM22 antibody MIP-1 alpha receptor antibody

P51681