Anti-beta-HCG Antibody (monoclonal) | Boster Immunoleader MA1111 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-beta-HCG Antibody (monoclonal)

catalog :

MA1111

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human

application :

immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-beta-HCG Antibody (monoclonal)

Catalog Number :

MA1111

Clonality :

Monoclonal (Clone: HCG-8)

Description short :

Mouse IgG monoclonal antibody for beta-HCG, chorionic gonadotropin, beta polypeptide (CGB) detection. Tested with IHC-P in Human. No cross reactivity with other proteins.

Price :

200 USD

Ig type :

Mouse IgG1

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human

Applications :

IHC-P

Immunohistochemistry(Paraffin-embedded S ... :

At 2μg/ml to detect β-HCG in formalin fixed and paraffin embedded tissues.

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

Purified human Chorionic Gonadotropin.

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Reconstitution :

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by SA1021 in IHC(P).

Background :

beta-HCG(beta-Human Chorionic Gonadotropin), also termed as Chorionic Gonadotropin, Beta Chain(CGB). It is encoded by a multigene cluster composed of six homologous sequences. And in the family of beta-containing glycoprotein hormones, beta-HCG is unique in that it contains an extension of 29 amino acids at its COOH end. beta-HCG is mapped to 19q13.32 and expressed in trophoblast and various malignant tumors promotes cellular motility in vivo. beta-HCG has a novel function in uterine adaptation to early pregnancy as well as in tumor development and underline the importance of HCG as an as yet unrecognized angiogenic factor.

Reference :

1. Bo, M.; Boime, I. : Identification of the transcriptionally active genes of the chorionic gonadotropin beta gene cluster in vivo. J. Biol. Chem. 267: 3179-3184, 1992.) 2. Policastro, P.; Ovitt, C. E.; Hoshina, M.; Fukuoka, H.; Boothby, M. R.; Biome, I. : The beta-subunit of human chorionic gonadotropin is encoded by multiple genes. J. Biol. Chem. 258: 11492-11499, 1983. 3. Zygmunt, M.; Herr, F.; Keller-Schoenwetter, S.; Kunzi-Rapp, K.; Munstedt, K.; Rao, C. V.; Lang, U.; Preissner, K. T. : Characterization of human chorionic gonadotropin as a novel angiogenic factor. J. Clin. Endocr. Metab. 87: 5290-5296, 2002.

Gene Name :

CGB

Protein Name :

Choriogonadotropin subunit beta

Gene Full Name :

chorionic gonadotropin, beta polypeptide

Synonyms :

CGB3 CGB5 CGB7 CGB8 hCGB CHORIONIC GONADOTROPIN, BETA POLYPEPTIDE 3

Uniprot ID :

Human(P01233)

more info or order :

Boster Immunoleader product webpage