Anti-Tyrosine Hydroxylase Antibody (monoclonal) | Boster Immunoleader MA1100 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Tyrosine Hydroxylase Antibody (monoclonal)

catalog :

MA1100

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Tyrosine Hydroxylase Antibody (monoclonal)

Catalog Number :

MA1100

Clonality :

Monoclonal (Clone: TH-100)

Description short :

Mouse IgG monoclonal antibody for Tyrosine Hydroxylase, tyrosine hydroxylase (TH) detection. Tested with WB, IHC-P, IHC-F in Human;rat;rabbit. No cross reactivity with other proteins.

Price :

200 USD

Ig type :

Mouse IgG1

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human, rat, rabbit.

Applications :

WB,IHC-P,IHC-F

Western blot :

At 0.25-0.5μg/ml with the appropriate system to detect tyrosine hydroxylase in cells and tissues.

Immunohistochemistry(Paraffin-embedded S ... :

At 0.5-1μg/ml to detect tyrosine hydroxylase in formalin fixed and paraffin embedded tissues.

Immunohistochemistry(Frozen Section) :

At 0.5-1μg/ml to detect tyrosine hydroxylase in formalin or acetone fixed tissues.

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

Rat tyrosine hydroxylase(TH).

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Reconstitution :

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1001 in WB, supported by SA1021 in IHC(P) and IHC(F).

Background :

Tyrosine hydroxylase is involved in the conversion of phenylalanine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Human TH gene contains 13 primary exons and spans approximately 8 kb. TH is in the 11p15.5 region.

Reference :

1. Brilliant, M. H.; Niemann, M. M.; Eicher, E. M. : urine tyrosine hydroxylase maps to the distal end of chromosome 7 within a region conserved in mouse and man. J. Neurogenet. 4: 259-266, 1987. 2. Craig, S. P.; Buckle, V. J.; Craig, I. W.; Lamouroux, A.; Mallet, J. : Localization of the human tyrosine hydroxylase gene to chromosome 11p15. (Abstract) Cytogenet. Cell Genet. 40: 610 only, 1985. 3. Craig, S. P.; Buckle, V. J.; Lamouroux, A.; Mallet, J.; Craig, I. : Localization of the human tyrosine hydroxylase gene to 11p15: gene duplication and evolution of metabolic pathways. Cytogenet. Cell Genet. 42: 29-32, 1986.

Gene Name :

Protein Name :

Tyrosine 3-monooxygenase

Gene Full Name :

tyrosine hydroxylase

Synonyms :

TYH DYT5b tyrosine 3-monooxygenase

Uniprot ID :

Human(P07101), Mouse(P24529), Rat(P04177)

more info or order :

Boster Immunoleader product webpage