Anti-Tryptophan Hydroxylase Antibody (monoclonal) | Boster Immunoleader MA1099 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Tryptophan Hydroxylase Antibody (monoclonal)

catalog :

MA1099

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Tryptophan Hydroxylase Antibody (monoclonal)

Catalog Number :

MA1099

Clonality :

Monoclonal (Clone: Try-63)

Description short :

Mouse IgG monoclonal antibody for Tryptophan Hydroxylase, tryptophan hydroxylase 1; tryptophan hydroxylase 2 (TPH1; TPH2) detection. Tested with WB in Human;rat;rabbit. No cross reactivity with other proteins.

Price :

200 USD

Ig type :

Mouse IgG3

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human, rat, rabbit.

Applications :

Western blot :

At 0.5-1μg/ml with the appropriate system to detect tryptophan hydroxylase in cells and tissues.

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

Recombinant rabbit tryptophan hydroxylase.

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Reconstitution :

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1001 in WB.

Background :

Tryptophan hydroxylase is the rate-limiting enzyme in the synthesis of serotonin(5-hydroxytryptamine, or 5HT). Tryptophan hydroxylase atalyzes the biopterin-dependent monooxygenation of tryptophan to5-hydroxytryptophan(5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. Human tryptophan hydroxylase(TPH) is mapped to chromosome 11p15.3-p14 by in situ hybridization.

Reference :

1. Craig, S. P.; Boularand, S.; Darmon, M. C.; Mallet, J.; Craig, I. W. : Localization of human tryptophan hydroxylase (TPH) to chromosome 11p15.3-p14 by in situ hybridization. Cytogenet. Cell Genet. 56: 157-159, 1991. 2. Nielsen, D. A.; Dean, M.; Goldman, D. : Genetic mapping of the human tryptophan hydroxylase gene on chromosome 11, using an intronic conformational polymorphism. Am. J. Hum. Genet. 51: 1366-1371, 1992.

Gene Name :

TPH1; TPH2

Protein Name :

Tryptophan 5-hydroxylase 1; Tryptophan 5-hydroxylase 2

Gene Full Name :

tryptophan hydroxylase 1; tryptophan hydroxylase 2

Synonyms :

TPH TPRH TRPH ADHD7 NTPH

Uniprot ID :

Human(P17752), Mouse(P17532), Rat(P09810), Human(Q8IWU9), Mouse(Q8CGV2), Rat(Q8CGU9)

more info or order :

Boster Immunoleader product webpage