Anti-Tau Antibody (monoclonal) | Boster Immunoleader MA1093 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Tau Antibody (monoclonal)

catalog :

MA1093

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse, rat, cow

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Tau Antibody (monoclonal)

Catalog Number :

MA1093

Clonality :

Monoclonal (Clone: TAU-93)

Description short :

Mouse IgG monoclonal antibody for Tau, microtubule-associated protein tau (MAPT) detection. Tested with WB, IHC-P in Human;mouse;rat. No cross reactivity with other proteins.

Price :

200 USD

Ig type :

Mouse IgG1

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human, bovine

Applications :

WB,IHC-P

Western blot :

At 0.5-1μg/ml with the appropriate system to detect Tau in cells and tissues.

Immunohistochemistry(Paraffin-embedded S ... :

At 1-2μg/ml to detect Tau in formalin fixed and paraffin embedded tissues.

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

Bovine microtubule-associated proteins(MAPs).

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Reconstitution :

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1001 in WB, supported by SA1021 in IHC(P).

Background :

The microtubule-associated proteins(MAPs) coassemble with tubulin into microtubules in vitro. Microtubule-associated protein tau appears to be enriched in axons. Tau are composed of 352 to 441 amino acids. The isoforms differ from each other by the presence or absence of 29-amino acid or 58-amino acid inserts located in the N terminus and a 31-amino repeat located in the C terminus. tau is important in establishing and maintaining neuronal morphology and is a major component of the neurofibrillary tangles(NFTs) characteristic of Alzheimer's brain. Microtubule-associated protein tau(MTBT1) is mapped to chromosome 17q21.

Reference :

1. Andreadis, A.; Brown, W. M.; Kosik, K. S. : Structure and novel exons of the human tau gene. Biochemistry 31: 10626-10633, 1992. 2. Donlon, T. A.; Harris, P.; Neve, R. L. : Localization of microtubule-associated protein tau (MTBT1) to chromosome 17q21. (Abstract) Cytogenet. Cell Genet. 46: 607, 1987.

Gene Name :

MAPT

Protein Name :

Microtubule-associated protein tau

Gene Full Name :

microtubule-associated protein tau

Synonyms :

DDPAC MAPTL PHF-tau FLJ31424 FTDP-17 MGC138549 MSTD MTBT1 MTBT2 PPND TAU G protein beta1/gamma2 subunit-interacting factor 1 microtubule-associated protein tau, isoform 4 Neurofibrillary tangle protein Paired helical filament-tau

Uniprot ID :

Human(P10636), Mouse(P10637), Rat(P19332)

more info or order :

Boster Immunoleader product webpage