Anti-S-100(beta-subunit) Antibody (monoclonal) | Boster Immunoleader MA1088 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-S-100(beta-subunit) Antibody (monoclonal)

catalog :

MA1088

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse, rat

application :

immunohistochemistry - paraffin section

publications citing this reagent :

SUN L, Zhao J, Zhang T, Qu L, Wang X, Xue B, et al. Protective effects of Salvianolic acid B on Schwann cells apoptosis induced by high glucose. Neurochem Res. 2012;37:996-1010 pubmed publisher
SUN L, Xue B, Li X, Wang X, Qu L, Zhang T, et al. Inhibitory effects of salvianolic acid B on apoptosis of Schwann cells and its mechanism induced by intermittent high glucose. Life Sci. 2012;90:99-108 pubmed publisher
Wang J, Zeng Y, Wu J, Li Y, Teng Y. Cograft of neural stem cells and schwann cells overexpressing TrkC and neurotrophin-3 respectively after rat spinal cord transection. Biomaterials. 2011;32:7454-68 pubmed publisher

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product information

Availability :

info changed 20150320

Product Name :

Anti-S-100(beta-subunit) Antibody (monoclonal)

Catalog Number :

MA1088

Clonality :

Monoclonal (Clone: SA-12)

Description short :

Mouse IgG monoclonal antibody for S-100 (beta-subunit), S100 calcium binding protein B (S100B) detection. Tested with IHC-P in Human;mouse;rat. No cross reactivity with other proteins.

Price :

200 USD

Ig type :

Mouse IgG1

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human, rabbit, rat

Applications :

IHC-P

Immunohistochemistry(Paraffin-embedded S ... :

At 1-2μg/ml to detect S-100b in formalin fixed and paraffin embedded tissues.

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

Bovine brain S-100b.

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Reconstitution :

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1001 in WB, supported by SA1021 in IHC(P).

Background :

S100 protein is a 21,000-Da component first isolated from brain by Moore(1965). Immunocytochemical studies demonstrated that S100 protein is produced by a wide variety of normal and neoplastic cells of mesodermal, neuroectodermal, and epithelial origin(Herrera et al., 1988). The S100 molecule is a dimer; thus there are 3 forms of S100: alpha-alpha, known as S-100a(0); alpha-beta, known as S-100a; and beta-beta, known as S-100b. S100 genes are clustered on human chromosome 1q21. S-100 protein expression by primary and metastatic adenocarcinomas.

Reference :

1. Engelkamp, D.; Schafer, B. W.; Mattei, M. G.; Erne, P.; Heizmann, C. W. : Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E. Proc. Nat. Acad. Sci. 90: 6547-6551, 1993. 2. Herrera, G. A.; Turbat-Herrera, E. A.; Lott, R. L. : S-100 protein expression by primary and metastatic adenocarcinomas. Am. J. Clin. Path. 89: 168-176, 1988.

Gene Name :

S100B

Protein Name :

Protein S100-B

Gene Full Name :

S100 calcium binding protein B

Synonyms :

NEF S100 S100-B S100beta S100 calcium binding protein, beta(neural) S-100 protein beta chain S-100 protein subunit beta

Uniprot ID :

Human(P04271), Mouse(P50114), Rat(P04631)

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