Anti-NCAM Antibody (monoclonal) | Boster Immunoleader MA1068 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-NCAM Antibody (monoclonal)

catalog :

MA1068

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-NCAM Antibody (monoclonal)

Catalog Number :

MA1068

Clonality :

Monoclonal (Clone: IML-43)

Description short :

Mouse IgG monoclonal antibody for NCAM, neural cell adhesion molecule 1 (NCAM1) detection. Tested with WB, ICC in Human;rat. No cross reactivity with other proteins.

Price :

200 USD

Ig type :

Mouse IgG1

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human, mouse, rat

Applications :

WB,ICC

Western blot :

At 4μg/ml with the appropriate system to detect NCAM in cells and tissues.

Immunocytochemistry :

Suitable

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

Growth cone enriched plasma membrane fraction from E17 rat forebrain.

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Reconstitution :

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1001 in WB, supported by SA1021 in ICC.

Background :

The neural cell adhesion molecule appears on early embryonic cells and is important in the formation of cell collectives and their boundaries at sites of morphogenesis. Later in development it is found on various differentiated tissues and is a major CAM mediating adhesion among neurons and between neurons and muscle. NCAM shares many features with immunoglobulins and is considered a member of the immunoglobulin superfamily NCAM gene is mapped to 11q23.1.

Reference :

1. Cunningham, B. A.; Hemperly, J. J.; Murray, B. A.; Prediger, E. A.; Brackenbury, R.; Edelman, G. M. : Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing. Science 236: 799-806, 1987. 2. D'Eustachio, P.; Owens, G. C.; Edelman, G. M.; Cunningham, B. A. : Chromosomal location of the gene encoding the neural cell adhesion molecule (N-CAM) in the mouse. Proc. Nat. Acad. Sci. 82: 7631-7635, 1985. 3. Nguyen, C.; Mattei, M. G.; Goridis, C.; Mattei, J. F.; Jordan, B. R. : Localization of the human N-CAM gene to chromosome 11 by in situ hybridization with a murine N-CAM cDNA probe. (Abstract) Cytogenet. Cell Genet. 40: 713 only, 1985.

Gene Name :

NCAM1

Protein Name :

Neural cell adhesion molecule 1

Gene Full Name :

neural cell adhesion molecule 1

Synonyms :

CD56 MSK39 N-CAM-1 NCAM ANTIGEN MSK39 IDENTIFIED BY MONOCLONAL ANTIBODY 5.1H11

Uniprot ID :

Human(P13591), Mouse(P13595), Rat(P13596)

more info or order :

Boster Immunoleader product webpage