Anti-Mucin Gastric Antibody (monoclonal) | Boster Immunoleader MA1061 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Mucin Gastric Antibody (monoclonal)

catalog :

MA1061

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Availability :

info changed 20150601

Product Name :

Anti-Mucin Gastric Antibody (monoclonal)

Catalog Number :

MA1061

Clonality :

Monoclonal (Clone: MG-31)

Description short :

Mouse IgG monoclonal antibody for Mucin Gastric, mucin 5AC, oligomeric mucus/gel-forming (MUC5AC) detection. Tested with WB, IHC-P, ICC in Human. No cross reactivity with other proteins.

Price :

200 USD

Ig type :

Mouse IgG1

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human, mouse, rabbit, rat

Applications :

WB,IHC-P,ICC

Western blot :

At 1-2μg/ml with the appropriate system to detect mucin gastric in cells and tissues.

Immunohistochemistry(Paraffin-embedded S ... :

At 2-4μg/ml to detect mucin gastric in formalin fixed and paraffin embedded tissues.

Immunocytochemistry :

Suitable

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

Mucin from human ovarian cyst fluid.

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Reconstitution :

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1001 in WB, supported by SA1021 in IHC(P) and ICC.

Background :

Mucin 5AC (Muc5AC) is a protein that in humans is encoded by the MUC5AC gene. Using real-time RT-PCR, Moehle et al. (2006) found that MUC5AC was highly expressed in adult trachea and stomach. Expression was lower in adult lung and weak in fetal lung, and no expression was detected in other tissues. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease. Moreover, Muc5ac is identified as a direct and critical mediator of resistance during intestinal nematode infection.

Reference :

1. Hasnain, S. Z., Evans, C. M., Roy, M., Gallagher, A. L., Kindrachuk, K. N., Barron, L., Dickey, B. F., Wilson, M. S., Wynn, T. A., Grencis, R. K., Thornton, D. J. Muc5ac: a critical component mediating the rejection of enteric nematodes. J. Exp. Med. 208: 893-900, 2011. 2. Moehle, C., Ackermann, N., Langmann, T., Aslanidis, C., Kel, A., Kel-Margoulis, O., Schmitz-Madry, A., Zahn, A., Stremmel, W., Schmitz, G. Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease. J. Molec. Med. 84: 1055-1066, 2006.

Gene Name :

MUC5AC

Protein Name :

Mucin-5AC

Gene Full Name :

mucin 5AC, oligomeric mucus/gel-forming

Synonyms :

Apomucin Gastric mucin LeB Lewis B blood group antigen Major Airway Glycoprotein MUC 5 MUC5 MUC5AC Mucin 5 subtype AC tracheobronchial Mucin 5 Subtypes A And C Mucin 5 subtypes A and C tracheobronchial/gastric Mucin 5AC Mucin 5AC oligomeric mucus/gel forming Mucin 5AC, oligomeric mucus/gel forming pseudogene TBM Tracheobronchial Mucin

Uniprot ID :

Human(P98088)

more info or order :

Boster Immunoleader product webpage