Anti-VEGFR2 Antibody (monoclonal) | Boster Immunoleader MA1040 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-VEGFR2 Antibody (monoclonal)

catalog :

MA1040

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse, rat

application :

immunohistochemistry - frozen section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-VEGFR2 Antibody (monoclonal)

Catalog Number :

MA1040

Clonality :

Monoclonal (Clone: FLK-6)

Description short :

Mouse IgG monoclonal antibody for VEGFR2, kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR) detection. Tested with WB, IHC-F in Human. No cross reactivity with other proteins.

Price :

200 USD

Ig type :

Mouse IgG1

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human

Applications :

IHC-F

Immunohistochemistry(Frozen Section) :

At 1-2μg/ml to detect VEGFR2 in formalin or acetone fixed tissues.

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

Recombinant human extracellular domain of VEGFR-2(KDR).

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Reconstitution :

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by SA1021 in IHC(F).

Background :

VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. The importance of VEGF and its receptor system in tumor growth and intervention in this system may provide promising approaches to cancer therapy. VEGF receptor 2 is a member of a receptor tyrosine kinase family. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues.

Reference :

1. Folkman, J. : Angiogenesis in cancer, vascular, rheumatoid and other disease. Nature Med. 1: 27-31, 1995. 2. Millauer, B.; Shawver, L. K.; Plate, K. H.; Risau, W.; Ullrich, A. : Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 367: 576-579, 1994.

Gene Name :

KDR

Protein Name :

Vascular endothelial growth factor receptor 2

Gene Full Name :

kinase insert domain receptor(a type III receptor tyrosine kinase)

Synonyms :

CD309 VEGFR FLK1 VEGFR2 TYROSINE KINASE GROWTH FACTOR RECEPTOR FLK1, MOUSE, HOMOLOG OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 Fetal liver kinase 1 Kinase insert domain receptor Protein-tyrosine kinase receptor flk-1

Uniprot ID :

Human(P35968), Mouse(P35918), Rat(O08775)

more info or order :

Boster Immunoleader product webpage