Anti-Elastin Antibody (monoclonal) | Boster Immunoleader MA1038 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Elastin Antibody (monoclonal)

catalog :

MA1038

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse, rat

application :

immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Elastin Antibody (monoclonal)

Catalog Number :

MA1038

Clonality :

Monoclonal (Clone: IL-4)

Description short :

Mouse IgG monoclonal antibody for Elastin, elastin (ELN ) detection. Tested with IHC-P in Human; dog; guinea pig. No cross reactivity with otherproteins.

Price :

200 USD

Ig type :

Mouse IgG1

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Bovine, human

Applications :

IHC-P

Immunohistochemistry(Paraffin-embedded S ... :

At 0.25-0.5μg/ml to detect elastin in formalin fixed and paraffin embedded tissues.

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

Bovine alpha-elastin.

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Reconstitution :

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by SA1021 in IHC(P).

Background :

Elastin is a major structural protein of tissues such as aorta, which must expand rapidly and recover completely. Elastin chains are cross-linked together into an extensible 3D network. It is a molecular determinant of late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle. Defects in elastin are a cause of autosomal dominant cutis laxa.

Reference :

1. Rosenbloom, J. : Personal Communication. Philadelphia, Pa., 4/1984 2. Urban, Z.; Riazi, S.; Seidl, T. L.; Katahira, J.; Smoot, L. B.; Chitayat, D.; Boyd, C. D.; Hinek, A. : Connection between elastin haploinsufficiency and increased cell proliferation in patients with supravalvular aortic stenosis and Williams-Beuren syndrome. Am. J. Hum. Genet. 71: 30-44, 2002. 3. Uitto, J.; Christiano, A. M.; Kahari, V.-M.; Bashir, M. M.; Rosenbloom, J. : Molecular biology and pathology of human elastin. Biochem. Soc. Trans. 19: 824-829, 1991.

Gene Name :

ELN

Protein Name :

Elastin

Gene Full Name :

elastin

Synonyms :

WS WBS SVAS Tropoelastin

Uniprot ID :

Human(P15502), Mouse(P11531), Rat(P11530)

more info or order :

Boster Immunoleader product webpage