Anti-CD4 Antibody (monoclonal) | Boster Immunoleader MA1016 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-CD4 Antibody (monoclonal)

catalog :

MA1016

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse, rat

application :

immunohistochemistry - frozen section

publications citing this reagent :

Zhao N, Li X, He X, Qiu Y, Zhu L, Qi F. Interleukin-15 gene therapy and the mammalian target of rapamycin inhibitor everolimus inhibit the growth of metastatic breast cancer. J Gene Med. 2013;15:366-74 pubmed publisher

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-CD4 Antibody (monoclonal)

Catalog Number :

MA1016

Clonality :

Monoclonal (Clone: CA-4)

Description short :

Mouse IgG monoclonal antibody for CD4, CD4 molecule (CD4) detection. Tested with IHC-F in Human. No cross reactivity with other proteins.

Price :

200 USD

Ig type :

Mouse IgG1

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human

Applications :

IHC-F

Immunohistochemistry(Frozen Section) :

At 1μg/ml to detect CD4 in formalin or acetone fixed tissues.

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

CD4-transfected mouse T-cell hybridoma, 3DT, followed by CD4+ human T-cell CEM cells.

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Reconstitution :

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by SA1021 in IHC(F).

Background :

CD stands for "cluster of differentiation"; the number that follows is arbitrarily assigned. In the full designation the cell type and nature and molecular weight of the antigen are given in brackets; for CD4, this is as follows: [T,gp55]. CD4 is present on a subset of T lymphocytes("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.

Reference :

1. Committee on Human Leukocyte Differentiation Antigens, IUIS WHO Nomenclature Subcommittee : Proposed nomenclature for human leukocyte differentiation antigens. Bull. WHO 5: 809-811, 1984. Note: Alternate: Immunology Today 5: 280 only, 1984. 2. Grakoui, A.; Bromley, S. K.; Sumen, C.; Davis, M. M.; Shaw, A. S.; Allen, P. M.; Dustin, M. L. : The immunological synapse: a molecular machine controlling T cell activation. Science 285: 221-227, 1999.

Gene Name :

CD4

Protein Name :

T-cell surface glycoprotein CD4

Gene Full Name :

CD4 molecule

Synonyms :

CD4 antigen T-cell surface antigen T4/Leu-3 T-cell surface glycoprotein CD4

Uniprot ID :

Human(P01730), Mouse(06332), Rat(05540)

more info or order :

Boster Immunoleader product webpage