Anti-Cathepsin D Antibody (monoclonal) | Boster Immunoleader MA1013 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Cathepsin D Antibody (monoclonal)

catalog :

MA1013

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Anti-Cathepsin D Antibody (monoclonal)

Catalog Number :

MA1013

Clonality :

Monoclonal (Clone: CP-D13)

Description short :

Mouse IgG monoclonal antibody for Cathepsin D, cathepsin D (CTSD) detection. Tested with WB, IHC-P in Human. No cross reactivity with other proteins.

Price :

200 USD

Ig type :

Mouse IgG2a

Size :

100 ug/vial

Form :

Lyophilized

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human

Applications :

WB,IHC-P

Western blot :

At 0.5-1μg/ml with the appropriate system to detect cathepsin D in cells and tissues.

Immunohistochemistry(Paraffin-embedded S ... :

At 1-2μg/ml to detect cathepsin D in formalin fixed and paraffin embedded tissues.

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

Human liver cathepsin D.

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Reconstitution :

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Storage :

At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1001 in WB, supported by SA1021 in IHC(P).

Background :

Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Cathepsin D is mapped to chromosome 11. The amino acid sequence predicted from the cDNA sequence shows that human cathepsin D consists of 412 amino acids with 20 and 44 amino acids in a pre- and a prosegment, respectively.

Reference :

1. Hasilik, A.; von Figura, K.; Grzeschik, K.-H. : Assignment of a gene for human cathepsin D to chromosome 11. (Abstract) Cytogenet. Cell Genet. 32: 284 only, 1982. 2. Qin, S.; Nakai, H.; Byers, M. G.; Eddy, R. L.; Haley, L. L.; Henry, W. M.; Wang, X.; Watkins, P. C.; Chirgwin, J. M.; Shows, T. B. : Mapping FSHB, CAT, and CTSD to specific sites on 11p. (Abstract) Cytogenet. Cell Genet. 46: 678 only, 1987. 3. Faust, P. L.; Kornfeld, S.; Chirgwin, J. M. : Cloning and sequence analysis of cDNA for human cathepsin D. Proc. Nat. Acad. Sci. 82: 4910-4914, 1985.

Gene Name :

CTSD

Protein Name :

Cathepsin D

Gene Full Name :

cathepsin D

Synonyms :

CLN10 CPSD cathepsin D(lysosomal aspartyl protease) ceroid-lipofuscinosis, neuronal 10

Uniprot ID :

Human(P07339), Mouse(P18242), Rat(P24268)

more info or order :

Boster Immunoleader product webpage