Anti-Caldesmon(smooth) Antibody (monoclonal) | Boster Immunoleader MA1009 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Caldesmon(smooth) Antibody (monoclonal)

catalog :

MA1009

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry - paraffin section

more info or order :

Boster Immunoleader product webpage

product information

Availability :

info changed 20150507

Product Name :

Anti-Caldesmon(smooth) Antibody (monoclonal)

Catalog Number :

MA1009

Clonality :

Monoclonal (Clone: CD-7)

Description short :

Mouse IgG monoclonal antibody for Caldesmon (smooth), caldesmon 1 (CALD1) detection. Tested with WB, IHC-F in Human;mouse;rat. No cross reactivity with other proteins.

Price :

200 USD

Ig type :

Mouse IgG1

Size :

100 ug/vial

Form :

Liquid

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human, mouse, rabbit

Applications :

WB,IHC-P

Western blot :

At 0.25-0.5μg/ml with the appropriate system to detect calcineurin alpha in cells and tissues.

Immunohistochemistry(Paraffin-embedded S ... :

At 0.5-1μg/ml to detect calcineurin alpha in formalin fixed and paraffin embedded tissues.

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

Human uterus smooth muscle extract.

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Storage :

At -20˚C for one year, at 4˚C for one month. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1001 in WB, supported by SA1021 in IHC(P).

Background :

Caldesmon is a potential actomyosin regulatory protein found in smooth muscle and nonmuscle cells. The predicted smooth-muscle polypeptide is 793 amino acids long. The high molecular weight caldesmon(h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon(l-CaD) is widely distributed in nonmuscle tissues and cells. Hayashi et al.(1992) demonstrated that the human CDM gene is composed of 14 exons.

Reference :

1. Humphrey, M. B.; Herrera-Sosa, H.; Gonzalez, G.; Lee, R.; Bryan, J. : Cloning of cDNAs encoding human caldesmons. Gene 112: 197-204, 1992. 2. Hayashi, K.; Yano, H.; Hashida, T.; Takeuchi, R.; Takeda, O.; Asada, K.; Takahashi, E.; Kato, I.; Sobue, K. : Genomic structure of the human caldesmon gene. Proc. Nat. Acad. Sci. 89: 12122-12126, 1992.

Gene Name :

CALD1

Protein Name :

Caldesmon

Gene Full Name :

caldesmon 1

Synonyms :

CDM H-CAD L-CAD

Uniprot ID :

Human(Q05682), Mouse(Q8VCQ8), Rat(Q62736)

more info or order :

Boster Immunoleader product webpage