Anti-Calcineurin alpha Antibody (monoclonal) | Boster Immunoleader MA1008 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

antibody

product name :

Anti-Calcineurin alpha Antibody (monoclonal)

catalog :

MA1008

quantity :

100 ug/vial

price :

200 USD

clonality :

monoclonal

host :

mouse

reactivity :

human, mouse, rat, cow

application :

western blot, immunohistochemistry - paraffin section

more info or order :

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product information

Availability :

info changed 20150507

Product Name :

Anti-Calcineurin alpha Antibody (monoclonal)

Catalog Number :

MA1008

Clonality :

Monoclonal (Clone: CC-6)

Description short :

Mouse IgG monoclonal antibody for Calcineurin alpha, protein phosphatase 3, regulatory subunit B, alpha (PPP3R1) detection. Tested with WB, IHC-P in Human;rat. No cross reactivity with other proteins.

Price :

200 USD

Ig type :

Mouse IgG1

Size :

100 ug/vial

Form :

Liquid

Specificity :

No cross reactivity with other proteins.

Reactivity :

Human, bovine, rat

Applications :

WB,IHC-P

Western blot :

At 0.25-0.5μg/ml with the appropriate system to detect calcineurin alpha in cells and tissues.

Immunohistochemistry(Paraffin-embedded S ... :

At 0.5-1μg/ml to detect calcineurin alpha in formalin fixed and paraffin embedded tissues.

Notes :

Other applications have not been tested. Optimal dilutions should be determined by end users.

Immunogen :

Bovine brain calcineurin.

Contents :

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Purification :

Ascites

Storage :

At -20˚C for one year, at 4˚C for one month. Avoid repeated freezing and thawing.

Relevant detection systems :

Boster provides a series of assays reacted with primary antibodies. Antibody can be supported by chemiluminescence kit EK1001 in WB, supported by SA1021 in IHC(P).

Background :

Calcineurin, the Ca(2+)/calmodulin-regulated protein phosphatase, first detected in skeletal muscle and brain, has been found in all cells from yeast to mammals. Calcineurin A alpha(PPP3CA),is located on human chromosomes 4, Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase(calcineurin) catalytic subunit. Calcineurin regulates bone formation by the osteoblast.

Reference :

1. Giri, P.; Higuchi, S.; Kincaid, R. L. : Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit. Biochem. Biophys. Res. Commun. 181: 252-258, 1991. 2. Sun, L.; Blair, H. C.; Peng, Y.; Zaidi, N.; Adebanjo, O. A.; Wu, X. B.; Wu, X. Y.; Iqbal, J.; Epstein, S.; Abe, E.; Moonga, B. S.; Zaidi, M. : Calcineurin regulates bone formation by the osteoblast. Proc. Nat. Acad. Sci. 102: 17130-17135, 2005. 3. Wang, M. G.; Yi, H.; Guerini, D.; Klee, C. B.; McBride, O. W. : Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and calcineurin B (PPP3R1) are located on human chromosomes 4, 10q21-q22 and 2p16-p15 respectively. Cytogenet. Cell Genet. 72: 236-241, 1996.

Gene Name :

PPP3R1

Protein Name :

Calcineurin subunit B type 1

Gene Full Name :

protein phosphatase 3, regulatory subunit B, alpha

Synonyms :

CNA2 CNB CNB1 CALNB1 Protein phosphatase 2B regulatory subunit 1 Protein phosphatase 3 regulatory subunit B alpha isoform 1

Uniprot ID :

Human(P63098), Mouse(Q63810), Rat(P63100)

more info or order :

Boster Immunoleader product webpage