Boster Immunoleader

ELISA/assay

Mouse CD5L PicoKine ELISA Kit

EK1414

1 x96 well plate

369 USD

Mouse CD5L PicoKine ELISA Kit

EK1414

369 USD

Sandwich ELISA kit for Quantitative Detection of Mouse CD5L

NSO,E22-V352

1 x96 well plate

156pg/ml-10,000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 485; Standard deviation: 20.37; CV(%): 4.2 Sample 2: n=16; Mean(ng/ml): 2021; Standard deviation: 70.74; CV(%): 3.5 Sample 3: n=16; Mean(ng/ml): 8472; Standard deviation: 432.07; CV(%): 5.1

Sample 1: n=24; Mean(ng/ml): 547; Standard deviation: 284.44; CV(%): 5.2 Sample 2: n=24; Mean(ng/ml): 2381; Standard deviation: 145.24; CV(%): 6.1 Sample 3: n=24; Mean(ng/ml): 8953; Standard deviation: 644.62; CV(%): 7.2

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of mouse CD5L in cell culture supernates, serum and plasma(heparin, EDTA).

Mouse

Catalog number Description Quantity - 96-well plate precoated with anti- mouse CD5L antibody 1 ST0000-10 Lyophilized recombinant mouse CD5Lstandard 10ng/tube×2 AR1107 Biotinylated anti- mouse CD5L antibody 130μl(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130μl(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

CD5 antigen-like, also known as Sp alpha and AIM, is a protein that in humans is encoded by the CD5L gene. It is mapped to 1q21-q23 by fluorescence in situ hybridization. It is found that Aim expression is induced in mouse macrophages in response to loading with highly oxidized low density lipoprotein (oxLDL), and that Aim is expressed in foam cells within atherosclerotic lesions. Both the expression of Aim in lesions and its induction by oxLDL require Lxr /Rxr heterodimers. Aim-null macrophages are highly susceptible to oxLDL-induced apoptosis in vitro and undergo accelerated apoptosis in atherosclerotic lesions in vivo. Double knockout of Aim and Ldlr reduce atherosclerotic lesions. Therefore, it is concluded that AIM expression protects macrophages from apoptosis within atherosclerotic lesions, promoting early lesion development.

CD5L

CD5 antigen-like

CD5 molecule-like

AAC-11 AIM API6 APOPTOSIS INHIBITOR 6 APOPTOSIS INHIBITOR OF MACROPHAGES CD5 antigen like (scavenger receptor cysteine rich family) CD5 antigen-like Cd5l CD5L_HUMAN CT 2 CT-2 Highly similar to ANTIGEN WC1.1 [Bos taurus] IgM associated peptide IgM-associated peptide Pdp PRO229 SCAVENGER RECEPTOR CYSTEINE-RICH FAMILY SP ALPHA SP-alpha Spalpha

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