Boster Immunoleader

ELISA/assay

Human Serpin C1/Antithrombin-III PicoKine ELISA Kit

EK1393

1 x96 well plate

369 USD

Human Serpin C1/Antithrombin-III PicoKine ELISA Kit

EK1393

369 USD

Sandwich ELISA kit for Quantitative Detection of Human Serpin C1/Antithrombin-III

NSO, H33-K464

1 x96 well plate

312pg/ml-20,000pg/ml

<10pg/ml

Sample 1: n=16; Mean(ng/ml): 1.05; Standard deviation: 0.064; CV(%): 6.1 Sample 2: n=16; Mean(ng/ml): 3.42; Standard deviation: 0.194; CV(%): 5.7 Sample 3: n=16; Mean(ng/ml): 8.67; Standard deviation: 0.546; CV(%): 6.3

Sample 1: n=24; Mean(ng/ml): 1.32; Standard deviation: 0.088; CV(%): 6.7 Sample 2: n=24; Mean(ng/ml): 3.74; Standard deviation: 0.239; CV(%): 6.4 Sample 3: n=24; Mean(ng/ml): 8.23; Standard deviation: 0.543; CV(%): 6.6

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human Serpin C1 in cell culture supernates, serum, plasma (heparin, EDTA, citrate) and urine.

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human Serpin C1 antibody 1 ST0000-20 Lyophilized recombinant human Serpin C1 standard 20ng/tube×2 AR1107 Biotinylated anti- human Serpin C1 antibody 130μl(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130μl(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Antithrombin III is the most important inhibitor of thrombin and other coagulation proteinases. It belongs to the serine proteinase inhibitor (serpin) superfamily of inhibitors and structurally related proteins, which contain reactive centers that have evolved to attract and entrap certain proteinases. Inherited antithrombin III deficiency (AT3D) is a risk factor for the early development of venous thromboembolism (THPH7). Antithrombin III regulates clot formation both by inhibiting thrombin activity directly and by interfering with earlier stages of the clotting cascade. By in situ hybridization and quantitative analysis of DNA dosage in carriers of chromosome 1 deletions, AT3 is mapped to 1q23-q25. The AT3 gene has 7 exons. It contains 9 complete and 1 partial repetitive ALU sequence elements, which occur in the introns of the gene at a higher frequency (about 22% of the intron sequence) than in the genome as a whole (about 5%).

SERPINC1

Antithrombin-III

serpin peptidase inhibitor, clade C (antithrombin), member 1

ANT3_HUMAN Antithrombin Antithrombin III Antithrombin-III AntithrombinIII AT 3 AT III AT3 AT3D ATIII Heparin cofactor I MGC22579 Serine (or cysteine) proteinase inhibitor clade C (antithrombin) member 1 Serine cysteine proteinase inhibitor clade C member 1 Serine proteinase inhibitor clade C member 1 Serpin C1 Serpin peptidase inhibitor clade C (antithrombin) member 1 SERPINC1 THPH7

P01008