Human TGFBR3 PicoKine ELISA Kit | Boster Immunoleader EK1383 product information

product summary

request information :

company name :

Boster Immunoleader

product type :

ELISA/assay

product name :

Human TGFBR3 PicoKine ELISA Kit

catalog :

EK1383

quantity :

1 x96 well plate

price :

369 USD

more info or order :

Boster Immunoleader product webpage

product information

Product Name :

Human TGFBR3 PicoKine ELISA Kit

Catalog Number :

EK1383

Price :

369 USD

Description short :

Sandwich ELISA kit for Quantitative Detection of Human TGFBR3

immunogen :

NSO, G21-D781

Pack Size :

1 x96 well plate

Assay Range :

156pg/ml-10,000pg/ml

Sensitivity :

<10pg/ml

Intra-Assay Precision :

Sample 1: n=16; Mean(ng/ml): 1.15; Standard deviation: 0.051; CV(%): 4.5 Sample 2: n=16; Mean(ng/ml): 2.52; Standard deviation: 0.108; CV(%): 4.3 Sample 3: n=16; Mean(ng/ml): 5.81; Standard deviation: 0.284; CV(%): 4.9

Inter-Assay Precision :

Sample 1: n=24; Mean(ng/ml): 1.63; Standard deviation: 0.109; CV(%): 6.7 Sample 2: n=24; Mean(ng/ml): 2.87; Standard deviation: 0.169; CV(%): 5.9 Sample 3: n=24; Mean(ng/ml): 5.66; Standard deviation: 0.401; CV(%): 7.1

Cross Reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Storage :

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Sample Type :

This kit is used for quantitative detection of human TGFBR3 in cell culture supernates, serum and plasma(heparin, EDTA).

Reactivity :

Human

Kit Components :

Catalog number Description Quantity - 96-well plate precoated with anti- human TGFBR3 antibody 1 ST0000-10 Lyophilized recombinant human TGFBR3 standard 10ng/tube×2 AR1107 Biotinylated anti- human TGFBR3 antibody 130μl(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130μl(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Background :

Betaglycan also known as Transforming growth factor beta receptor III (TGFBR3), is a cell- surfacechondroitin sulfate / heparan sulfate proteoglycan >300 kDa in molecular weight. Betaglycan binds to various members of the TGF-beta superfamily of ligands via its core protein, and bFGF via its heparan sulfate chains. It is not involved directly in TGF-beta signal transduction but by binding to various member of the TGF-beta superfamily at the cell surface it acts as a reservoir of ligand for TGF-beta receptors. By cDNA array and immunohistochemistry analyses, it is found that TGFBR3 expression is lost in most breast cancers examined in association with loss of heterozygosity of the TGFBR3 locus. TGFBR3 expression decreased during breast cancer progression, and low levels predicted decreased recurrence-free survival in patients. Loss of TGFBR3 through allelic imbalance is a frequent genetic event during breast cancer development that increases metastatic potential. Also, TGFBR3 can localize transformation in the heart and play an essential, nonredundant role in TGF-beta signaling.

Gene Name :

TGFBR3

Protein Name :

Transforming growth factor beta receptor type 3

Gene Full Name :

transforming growth factor, beta receptor III

Synonyms :

Beta glycan Betaglycan Betaglycan proteoglycan BGCAN TGBR3_HUMAN TGF beta receptor type 3 TGF beta receptor type III TGF-beta receptor type 3 TGF-beta receptor type III TGFB R3 TGFBR 3 TGFBR3 TGFR 3 TGFR-3 TGFR3 Transforming growth factor beta receptor III Transforming growth factor beta receptor III betaglycan 300kDa Transforming growth factor beta receptor type 3

Uniprot IDs :

Q03167

more info or order :

Boster Immunoleader product webpage