Boster Immunoleader

ELISA/assay

Human Neuregulin-1/NRG1-beta1 PicoKine ELISA Kit

EK1378

1 x96 well plate

369 USD

Human Neuregulin-1/NRG1-beta1 PicoKine ELISA Kit

EK1378

369 USD

Sandwich ELISA kit for Quantitative Detection of Human Neuregulin-1/NRG1-beta1

E.coli, S2-K246

1 x96 well plate

62.5pg/ml-4000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 675; Standard deviation: 28.35; CV(%): 4.2 Sample 2: n=16; Mean(pg/ml): 1308; Standard deviation: 61.48; CV(%): 4.7 Sample 3: n=16; Mean(pg/ml): 2147; Standard deviation: 113.8; CV(%): 5.3

Sample 1: n=24; Mean(pg/ml): 694; Standard deviation: 40.25; CV(%): 5.8 Sample 2: n=24; Mean(pg/ml): 1382; Standard deviation: 84.3; CV(%): 6.1 Sample 3: n=24; Mean(pg/ml): 2503; Standard deviation: 172.7; CV(%): 6.9

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human Neuregulin-1 in cell culture supernates, serum and plasma(heparin, EDTA).

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human Neuregulin-1 antibody 1 ST0000-10 Lyophilized recombinant human Neuregulin-1 standard 10ng/tube×2 AR1107 Biotinylated anti- human Neuregulin-1 antibody 130μl(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130μl(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Neuregulin 1 or NRG1 is a protein that in humans is encoded by the NRG1 gene. It is mapped to 8p12. NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). It is also essential for the normal development of the nervous system and the heart. Furthermore, it was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues.

NRG1

Pro-neuregulin-1, membrane-bound isoform

neuregulin 1

Acetylcholine receptor inducing activity Acetylcholine receptor-inducing activity ARIA Breast cancer cell differentiation factor p45 GGF GGF2 Glial growth factor Heregulin HGL HRG HRG1 HRGA MST131 NDF Neu differentiation factor Neuregulin 1 Neuregulin-1 Neuregulin1 nrg1 NRG1 beta 1 NRG1_HUMAN Pro neuregulin 1 Pro NRG1 Pro-NRG1 Sensory and motor neuron derived factor Sensory and motor neuron-derived factor SMDF

Q02297