Boster Immunoleader

ELISA/assay

Mouse FGF23 PicoKine ELISA Kit

EK1362

1 x96 well plate

369 USD

Mouse FGF23 PicoKine ELISA Kit

EK1362

369 USD

Sandwich ELISA kit for Quantitative Detection of Mouse FGF23

E.coli, Y25-V251

1 x96 well plate

15.6pg/ml-1000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 37.7; Standard deviation: 1.39; CV(%): 3.7 Sample 2: n=16; Mean(pg/ml): 118; Standard deviation: 5.43; CV(%): 4.6 Sample 3: n=16; Mean(pg/ml): 621; Standard deviation: 32.91; CV(%): 5.3

Sample 1: n=24; Mean(pg/ml): 38.2; Standard deviation: 2.56; CV(%): 6.7 Sample 2: n=24; Mean(pg/ml): 128; Standard deviation: 8.70; CV(%): 6.8 Sample 3: n=24; Mean(pg/ml): 642; Standard deviation: 49.43; CV(%): 7.7

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of mouse FGF23 in cell culture supernates, serum and plasma(heparin, EDTA).

Mouse

Catalog number Description Quantity - 96-well plate precoated with anti- mouse FGF23 antibody 1 ST0000-10 Lyophilized recombinant mouse FGF23 standard 10ng/tube×2 AR1107 Biotinylated anti- mouse FGF23 antibody 130μl(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130μl(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Fibroblast growth factor 23 or FGF23 is a protein that in humans is encoded by the FGF23 gene. It is a member of the fibroblast growth factor (FGF) family which is responsible for phosphate metabolism. The main function of FGF23 seems to be regulation of phosphate concentration in plasma. FGF23 is secreted by Osteocytes in response to elevated Calcitriol. And it acts on the kidneys, where it decreases the expression of NPT2, a sodium-phosphate cotransporter in the proximal tubule. Thus, FGF23 decreases the reabsorption and increases excretion of phosphate. Also, FGF23 may suppress 1-alpha-hydroxylase, reducing its ability to activate vitamin D and subsequently impairing calcium absorption.

FGF23

Fibroblast growth factor 23

fibroblast growth factor 23

ADHR FGF-23 Fgf23 FGF23_HUMAN FGFN Fibroblast growth factor 23 Fibroblast growth factor 23 C-terminal peptide Fibroblast growth factor 23 precursor HPDR2 HYPF Phosphatonin PHPTC Tumor derived hypophosphatemia inducing factor Tumor-derived hypophosphatemia-inducing factor

Q9EPC2