Boster Immunoleader

ELISA/assay

Rat Neuropilin-2 PicoKine ELISA Kit

EK1345

1 x96 well plate

369 USD

Rat Neuropilin-2 PicoKine ELISA Kit

EK1345

369 USD

Sandwich ELISA kit for Quantitative Detection of Rat Neuropilin-2

NSO, Q23-D857

1 x96 well plate

156pg/ml-10,000pg/ml

<10pg/ml

Sample 1: n=16; Mean(ng/ml): 1.6; Standard deviation: 0.058; CV(%): 3.6 Sample 2: n=16; Mean(ng/ml): 3.5; Standard deviation: 0.161; CV(%): 4.6 Sample 3: n=16; Mean(ng/ml): 6.1; Standard deviation: 0.317; CV(%): 5.2

Sample 1: n=24; Mean(ng/ml): 1.9; Standard deviation: 0.089; CV(%): 4.7 Sample 2: n=24; Mean(ng/ml): 4.2; Standard deviation: 0.231; CV(%): 5.5 Sample 3: n=24; Mean(ng/ml): 7.3; Standard deviation: 0.467; CV(%): 6.4

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of rat Neuropilin-2 in cell culture supernates, cell lysates and tissue homogenates.

Rat

Catalog number Description Quantity - 96-well plate precoated with anti- rat Neuropilin-2 antibody 1 ST0000-10 Lyophilized recombinant rat Neuropilin-2standard 10ng/tubex2 AR1107 Biotinylated anti- rat Neuropilin-2 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

NRP2(Neuropilin-2), also called Npn2 or VEGF165R2, encodes a member of the neuropilin family of receptor proteins. The soluble NRP2 was secreted as a 62.5-kD protein following transfection in Chinese hamster ovary cells. The NRP2 gene is mapped to 2q33.3. The NRP2 gene contains 17 exons and spans about 112 kb. This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Mice with null mutations in genes encoding Sema3F, and its holoreceptor components Npn2 and plexin A3 (PLEXA3), exhibit increased dentate gyrus granule cell and cortical layer V pyramidal neuron spine number and size, and also aberrant spine distribution. Moreover, Sema3F promotes loss of spines and excitatory synapses in dissociated neurons in vitro, and in NRP2-null brain slices cortical layer V and dentate gyrus granule cells exhibit increased miniature excitatory postsynaptic current frequency. These disparate effects of secreted semaphorins are reflected in the restricted dendritic localization of NRP2 to apical dendrites and of Npn1 to all dendrites of cortical pyramidal neurons.

NRP2

Neuropilin-2

neuropilin 2

MGC126574 Neuropilin 2 Neuropilin-2 Neuropilin2 NP 2 NP2 NPN 2 NPN2 NRP 2 Nrp2 NRP2_HUMAN PRO2714 Receptor for VEGF165 and semaphorins class3 Vascular endothelial cell growth factor 165 receptor 2 Vascular endothelial growth factor 165 receptor 2 VEGF1265R2 VEGF165R2

O35276