Boster Immunoleader

ELISA/assay

Human SLAM/CD150 PicoKine ELISA Kit

EK1321

1 x96 well plate

369 USD

Human SLAM/CD150 PicoKine ELISA Kit

EK1321

369 USD

Sandwich ELISA kit for Quantitative Detection of Human SLAM/CD150

NSO, A21-K236

1 x96 well plate

156pg/ml-10,000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 1281; Standard deviation: 87.11; CV(%): 6.8 Sample 2: n=16; Mean(pg/ml): 3355; Standard deviation: 164.4; CV(%): 4.9 Sample 3: n=16; Mean(pg/ml): 5633; Standard deviation: 310; CV(%): 5.5

Sample 1: n=24; Mean(pg/ml): 1426; Standard deviation: 108.4; CV(%): 7.6 Sample 2: n=24; Mean(pg/ml): 3865; Standard deviation: 201; CV(%): 5.2 Sample 3: n=24; Mean(pg/ml): 6134; Standard deviation: 392.6; CV(%): 6.4

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human SLAM in cell culture supernates, serum and plasma(heparin, EDTA).

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human SLAM antibody 1 ST0000-10 Lyophilized recombinant human SLAM standard 10ng/tubex2 AR1107 Biotinylated anti- human SLAM antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Signaling lymphocytic activation molecule is a protein that in humans is encoded by the SLAMF1 gene. It belongs to the immunoglobulin gene superfamily. This gene is mapped to 1q23.3. It has found that SLAM is constitutively expressed on peripheral blood memory T cells, T-cell clones, immature thymocytes and a proportion of B cells, and is rapidly induced on naive T cells after activation. In MV-resistant cell lines, infection with clinical MV and expression of SLAM, but not CD46, caused cytopathic effects (CPE). The expression of SLAM on activated B and T lymphocytes correlates with the pathology of MV infection in humans and monkeys, in which lymphoid organs are the chief sites of MV replication and the binding of MV to SLAM may impair the signaling functions of SLAM in lymphocyte activation and inhibit Th0/Th1 cytokine production, thereby promoting Th2 cytokine production. It has reported that antibody-mediated ligation of SLAM on thymocytes triggered a protein tyrosine phosphorylation signal in T cells in a SAP-dependent manner. This signal also involved SHIP, the adaptor molecules DOK2, DOK1, and SHC and RASGAP.

SLAMF1

Signaling lymphocytic activation molecule

signaling lymphocytic activation molecule family member 1

4933415F16 AA177906 CD 150 Cd150 CD150 antigen Cdw150 Estm51 Ipo 3 IPO-3 Ipo3 MGC151472 MGC151476 OTTHUMP00000025670 OTTHUMP00000060252 RGD1560634 Signaling lymphocytic activation molecule Signaling lymphocytic activation molecule family member 1 Signaling lymphocytic activation molecule family member 1, isoform CRA_a Signaling lymphocytic activation molecule family member 1, isoform CRA_b Signaling lymphocytic activation molecule precursor Slaf1 SLAF1_HUMAN SLAM family, member 1 Slamf 1 Slamf1 SLAMF1 protein

Q13291