Boster Immunoleader

ELISA/assay

Human TGFBR2 PicoKine ELISA Kit

EK1307

1 x96 well plate

369 USD

Human TGFBR2 PicoKine ELISA Kit

EK1307

369 USD

Sandwich ELISA kit for Quantitative Detection of Human TGFBR2

NSO, I24-D159

1 x96 well plate

15.6pg/ml-1000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 175; Standard deviation: 7.9; CV(%): 4.5 Sample 2: n=16; Mean(pg/ml): 460; Standard deviation: 17.48; CV(%): 3.8 Sample 3: n=16; Mean(pg/ml): 671; Standard deviation: 34.9; CV(%): 5.2

Sample 1: n=24; Mean(pg/ml): 254; Standard deviation: 13.7; CV(%): 5.4 Sample 2: n=24; Mean(pg/ml): 482; Standard deviation: 23.6; CV(%): 4.9 Sample 3: n=24; Mean(pg/ml): 715; Standard deviation: 45; CV(%): 6.3

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human TGFBR2 in cell culture supernates, serum and plasma(heparin, EDTA).

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human TGFBR2 antibody 1 ST0000-10 Lyophilized recombinant human TGFBR2 standard 10ng/tubex2 AR1107 Biotinylated anti- human TGFBR2 antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

TGFBR2(transforming growth factor, beta receptor II (70/80kDa)), also known as TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II( TGF-beta receptor type II, TbetaR-II), is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. A TGFBR2 cDNA encoding a deduced 565-amino acid protein with a calculated molecular mass of approximately 60 kD in length. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different informs have been characterized. TGFBR2 may be a target of the EWS-FLI1 fusion protein found in Ewing sarcoma and related peripheral primitive neuroectodermal tumors.

TGFBR2

TGF-beta receptor type-2

transforming growth factor, beta receptor II (70/80kDa)

AAT3 FAA3 LDS1B LDS2 LDS2B MFS2 RIIC TAAD2 TbetaR-II TGF-beta receptor type II TGF-beta receptor type-2 TGF-beta type II receptor TGFbeta RII Tgfbr2 TGFR 2 TGFR-2 TGFR2_HUMAN Transforming growth factor beta receptor II (70/80kDa) Transforming growth factor-beta receptor type II

P37173