Boster Immunoleader

ELISA/assay

Human Corin PicoKine ELISA Kit

EK1283

1 x96 well plate

369 USD

Human Corin PicoKine ELISA Kit

EK1283

369 USD

Sandwich ELISA kit for Quantitative Detection of Human Corin

NSO, S67-N1042

1 x96 well plate

62.5pg/ml-4000pg/ml

<10pg/ml

Sample 1: n=16; Mean(pg/ml): 1032; Standard deviation: 36.12; CV(%): 3.5 Sample 2: n=16; Mean(pg/ml): 2355; Standard deviation: 89.49; CV(%): 3.8 Sample 3: n=16; Mean(pg/ml): 3568; Standard deviation: 146; CV(%): 4.1

Sample 1: n=24; Mean(pg/ml): 897; Standard deviation: 42.2; CV(%): 4.7 Sample 2: n=24; Mean(pg/ml): 2018; Standard deviation: 131.17; CV(%): 6.5 Sample 3: n=24; Mean(pg/ml): 3465; Standard deviation: 249.48; CV(%): 7.2

There is no detectable cross-reactivity with other relevant proteins.

Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

This kit is used for quantitative detection of human Corin in cell culture supernates, serum, plasma(heparin, EDTA) and tissue homogenates.

Human

Catalog number Description Quantity - 96-well plate precoated with anti- human Corin antibody 1 ST0000-4 Lyophilized recombinant human Corin standard 4ng/tubex2 AR1107 Biotinylated anti- human Corin antibody 130ul(dilution 1:100) AR1103 Avidin-Biotin-Peroxidase Complex (ABC) 130ul(dilution 1:100) AR1106-1 Sample diluent buffer 30 ml AR1106-2 Antibody diluent buffer 12ml AR1106-3 ABC diluent buffer 12ml AR1104 TMB color developing agent 10ml AR1105 TMB stop solution 10ml

Atrial natriuretic peptide-converting enzyme, also called CRN or ATC2, is a protein that in humans is encoded by the CORIN gene. It is mapped to 4p12. This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. It has been found that Corin is the pro-ANP-converting enzyme and that Corin-mediated pro-ANP activation may play a role in regulating blood pressure. What’s more, Corin and ANP are essential for physiologic changes at the maternal-fetal interface. This protein may also function as a pro-brain-type natriuretic peptide convertase. Corin gene mutations which cause Corin to impair activity might be an underlying mechanism in hypertension.

CORIN

Atrial natriuretic peptide-converting enzyme

corin, serine peptidase

activated protease fragment ATC 2 ATC2 Atrial natriuretic peptide-converting enzyme Atrial natriuteric peptide converting enzyme Corin Corin serine peptidase CORIN_HUMAN CRN Heart specific serine proteinase Heart specific serine proteinase ATC2 Heart-specific serine proteinase ATC2 Lrp 4 Lrp4 MGC119742 Pro ANP convertase Pro ANP converting enzyme Pro-ANP-converting enzyme TMPRSS 10 TMPRSS10 Transmembrane protease serine 10

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